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ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression

The expression of Igf2 in mammals shows a complex regulation involving multiple promoters and epigenetic mechanisms. We previously identified a novel regulatory mechanism based on the interaction between the transcriptional factor ZBED6 and Igf2 intron. Disruption of the ZBED6-Igf2 interaction leads...

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Detalles Bibliográficos
Autores principales: Naboulsi, Rakan, Larsson, Mårten, Andersson, Leif, Younis, Shady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484269/
https://www.ncbi.nlm.nih.gov/pubmed/34593874
http://dx.doi.org/10.1038/s41598-021-98777-0

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