Cargando…

Key Clinical Adverse Events in Patients with Advanced Basal Cell Carcinoma Treated with Sonidegib or Vismodegib: A Post Hoc Analysis

INTRODUCTION: Sonidegib is approved to treat locally advanced basal cell carcinoma (laBCC) in the USA, EU, Switzerland, and Australia and metastatic basal cell carcinoma (mBCC) in Switzerland and Australia in patients not amenable to surgery or radiotherapy. Vismodegib is approved to treat patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutzmer, Ralf, Loquai, Carmen, Robert, Caroline, Dréno, Brigitte, Guminski, Alexander, Lewis, Karl, Arntz, Ramon, Martelli, Serena, Squittieri, Nicholas, Kheterpal, Meenal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484385/ https://www.ncbi.nlm.nih.gov/pubmed/34490549 http://dx.doi.org/10.1007/s13555-021-00588-8

Ejemplares similares

Assessment of various efficacy outcomes using ERIVANCE-like criteria in patients with locally advanced basal cell carcinoma receiving sonidegib: results from a preplanned sensitivity analysis
por: Gutzmer, Ralf, et al.
Publicado: (2021)

Sonidegib improved quality of life in patients with advanced basal cell carcinoma: Results from the phase 2 Basal cell carcinoma outcomes with LDE225 treatment trial through 73 weeks
por: Migden, Michael, et al.
Publicado: (2022)

Expression of Glioma-associated oncogene homolog 1 as biomarker with sonidegib in advanced basal cell carcinoma
por: Dummer, Reinhard, et al.
Publicado: (2020)

A Matching-Adjusted Indirect Comparison of Sonidegib and Vismodegib in Advanced Basal Cell Carcinoma
por: Odom, Dawn, et al.
Publicado: (2017)

Benefit–risk assessment of sonidegib and vismodegib in the treatment of locally advanced basal cell carcinoma
por: García Ruiz, Antonio J, et al.
Publicado: (2022)

Effects of Sonidegib Following Dose Reduction and Treatment Interruption in Patients with Advanced Basal Cell Carcinoma During 42-Month BOLT Trial
por: Lewis, Karl, et al.
Publicado: (2021)

Intracranial regression of an advanced basal cell carcinoma using sonidegib and itraconazole after failure with vismodegib
por: Yoon, Jaeyoung, et al.
Publicado: (2017)

Sonidegib after vismodegib discontinuation in a patient with Gorlin–Goltz syndrome and multiple basal cell carcinomas
por: Piccerillo, Alfredo, et al.
Publicado: (2021)

Sustained Suppression of Gorlin Syndrome-Associated Basal Cell Carcinomas with Vismodegib or Sonidegib: A Case Series
por: Wescott, Raquel, et al.
Publicado: (2023)

Tolerance of sonidegib after intolerance of vismodegib—Experience in two patients with nevoid basal cell carcinoma syndrome (Gorlin syndrome)
por: Venturi, Federico, et al.
Publicado: (2023)

Long‐term efficacy and safety of sonidegib in patients with advanced basal cell carcinoma: 42‐month analysis of the phase II randomized, double‐blind BOLT study
por: Dummer, R., et al.
Publicado: (2019)

Long‐term efficacy and safety of sonidegib in patients with locally advanced and metastatic basal cell carcinoma: 30‐month analysis of the randomized phase 2 BOLT study
por: Lear, J.T., et al.
Publicado: (2017)

Evaluation of Hedgehog Pathway Inhibition on Nevoid Basal Cell Carcinoma Syndrome Fibroblasts and Basal Cell Carcinoma-Associated Fibroblasts: Are Vismodegib and Sonidegib Useful to Target Cancer-Prone Fibroblasts?
por: Eibenschutz, Laura, et al.
Publicado: (2021)

Sonidegib for the Treatment of Advanced Basal Cell Carcinoma
por: Brancaccio, Gabriella, et al.
Publicado: (2020)

Efficacy and Safety of Sonidegib in Adult Patients with Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome): Results from a Phase 2, Double-Blind, Randomized Trial
por: Lear, John T, et al.
Publicado: (2020)

Vismodegib: the Proof of Concept in Basal Cell Carcinoma
por: Berrada, Narjiss, et al.
Publicado: (2014)

Sonidegib: Safety and Efficacy in Treatment of Advanced Basal Cell Carcinoma
por: Villani, Alessia, et al.
Publicado: (2020)

Giant basal cell carcinoma of the vulva successfully treated with Sonidegib
por: Camela, Elisa, et al.
Publicado: (2022)

Sonidegib treatment in patients with locally advanced basal cell carcinoma
por: Villani, Alessia, et al.
Publicado: (2022)

Phase I and phase II sonidegib and vismodegib clinical trials for the treatment of paediatric and adult MB patients: a systemic review and meta-analysis
por: Li, Yuchen, et al.
Publicado: (2019)

Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
por: Yurchenko, Andrey A., et al.
Publicado: (2022)

Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma
por: Wahid, Mohd, et al.
Publicado: (2017)

Effective systemic treatment of advanced periocular basal cell carcinoma with sonidegib
por: Rokohl, Alexander C., et al.
Publicado: (2021)

Sonidegib with and Without Adjunctive Treatment for Locally Advanced Basal Cell Carcinomas
por: Villani, Alessia, et al.
Publicado: (2022)

Experience with sonidegib in patients with advanced basal cell carcinoma: case reports
por: Puig, Susana, et al.
Publicado: (2022)

Treatment of periocular basal cell carcinoma with neoadjuvant vismodegib
por: Su, Maxwell G., et al.
Publicado: (2020)

Treatment of Locally Advanced Basal Cell Carcinomas with Vismodegib
por: Mastronardi, Luis, et al.
Publicado: (2021)

Vismodegib in Locally Advanced Basal Cell Carcinoma in Slovenia
por: Mesti, Tanja, et al.
Publicado: (2022)

Effectiveness, Safety and Utilization of Vismodegib for Locally Advanced Basal Cell Carcinoma Under Real-world Conditions: Non-interventional Cohort Study JONAS
por: KAATZ, Martin, et al.
Publicado: (2022)

Sonidegib, a novel smoothened inhibitor for the treatment of advanced basal cell carcinoma
por: Doan, Hung Q, et al.
Publicado: (2016)

Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas
por: Jain, Sachin, et al.
Publicado: (2017)

Sonidegib‐induced muscle spasms in the treatment of basal cell carcinoma: Strategies to adopt
por: Villani, Alessia, et al.
Publicado: (2022)

Clinical Clearance Following Improvement of Histologic Subtype of Basal Cell Carcinoma with Sonidegib
por: LEOW, Liang Joo, et al.
Publicado: (2022)

Sonidegib in the Treatment of Locally Advanced Basal Cell Carcinoma: A Retrospective Study
por: HERMS, Florian, et al.
Publicado: (2022)

Targeted Therapy for Advanced Basal-Cell Carcinoma: Vismodegib and Beyond
por: Cowey, C. Lance
Publicado: (2013)

Investigational agents in metastatic basal cell carcinoma: focus on vismodegib
por: Batty, Nicolas, et al.
Publicado: (2012)

Basal cell carcinoma: multimodal treatment and the role of neoadjuvant vismodegib
por: Martins, Pedro Carvalho, et al.
Publicado: (2019)

First reported case of concurrent sonidegib and radiotherapy for recurrent, advanced basal cell carcinoma
por: Wang, Kaidi, et al.
Publicado: (2021)

The Efficacy of Sonidegib in Treating Locally Advanced Basal Cell Carcinoma Involving the Periocular Area
por: Villani, Alessia, et al.
Publicado: (2023)

18-FDG PET/CT assessment of basal cell carcinoma with vismodegib
por: Thacker, Curtis A, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gb7rhato07h1ha8b6s3kru7u66