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Patient Journey in Atopic Dermatitis: The Real-World Scenario

INTRODUCTION: The diagnosis and management of atopic dermatitis (AD) is extensively addressed in detailed clinical guidelines. However, the high heterogeneity regarding presentation and progression and the increasingly broad therapeutic landscape suggest a complex real-world scenario, leading to mul...

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Autores principales: Carrascosa, Jose Manuel, de la Cueva, Pablo, de Lucas, Raul, Fonseca, Eduardo, Martín, Ana, Vicente, Asunción, Fortes, Maria Pilar, Gómez, Susana, Rebollo, Francisco José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484426/
https://www.ncbi.nlm.nih.gov/pubmed/34426957
http://dx.doi.org/10.1007/s13555-021-00592-y
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author Carrascosa, Jose Manuel
de la Cueva, Pablo
de Lucas, Raul
Fonseca, Eduardo
Martín, Ana
Vicente, Asunción
Fortes, Maria Pilar
Gómez, Susana
Rebollo, Francisco José
author_facet Carrascosa, Jose Manuel
de la Cueva, Pablo
de Lucas, Raul
Fonseca, Eduardo
Martín, Ana
Vicente, Asunción
Fortes, Maria Pilar
Gómez, Susana
Rebollo, Francisco José
author_sort Carrascosa, Jose Manuel
collection PubMed
description INTRODUCTION: The diagnosis and management of atopic dermatitis (AD) is extensively addressed in detailed clinical guidelines. However, the high heterogeneity regarding presentation and progression and the increasingly broad therapeutic landscape suggest a complex real-world scenario, leading to multiple trajectories of AD patients. METHODS: Using a Delphi methodology for assessing the degree of consensus, we explored the views of a panel of dermatologists regarding the patients’ trajectory through the diagnosis (block 1), treatment (block 2), and long-term management (block 3) of AD. Based on a systematic search of the literature, a scientific committee prepared a questionnaire of relevant items that were rated on a 10-point scale (from “totally agree” to “totally disagree”) by a panel of dermatologists attending patients with AD in the hospital setting. Consensus was established based on predefined rules. RESULTS: The final questionnaire included 58 items and was answered by 17 dermatologists. Overall, consensus was reached on 22 items (37.9%), each of which was a consensus for agreement. The consensus rates in blocks 1, 2, and 3 were 22.7%, 19.0%, and 86%, respectively. CONCLUSIONS: Our analysis revealed a remarkable lack of consensus on various aspects of the routine diagnosis and treatment of AD. These findings suggest the presence of unmet needs or limited implementation of guidelines for the management of AD and encourage further research to explore the causes of this low consensus on the management of AD in the real-world setting. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13555-021-00592-y.
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spelling pubmed-84844262021-10-08 Patient Journey in Atopic Dermatitis: The Real-World Scenario Carrascosa, Jose Manuel de la Cueva, Pablo de Lucas, Raul Fonseca, Eduardo Martín, Ana Vicente, Asunción Fortes, Maria Pilar Gómez, Susana Rebollo, Francisco José Dermatol Ther (Heidelb) Original Research INTRODUCTION: The diagnosis and management of atopic dermatitis (AD) is extensively addressed in detailed clinical guidelines. However, the high heterogeneity regarding presentation and progression and the increasingly broad therapeutic landscape suggest a complex real-world scenario, leading to multiple trajectories of AD patients. METHODS: Using a Delphi methodology for assessing the degree of consensus, we explored the views of a panel of dermatologists regarding the patients’ trajectory through the diagnosis (block 1), treatment (block 2), and long-term management (block 3) of AD. Based on a systematic search of the literature, a scientific committee prepared a questionnaire of relevant items that were rated on a 10-point scale (from “totally agree” to “totally disagree”) by a panel of dermatologists attending patients with AD in the hospital setting. Consensus was established based on predefined rules. RESULTS: The final questionnaire included 58 items and was answered by 17 dermatologists. Overall, consensus was reached on 22 items (37.9%), each of which was a consensus for agreement. The consensus rates in blocks 1, 2, and 3 were 22.7%, 19.0%, and 86%, respectively. CONCLUSIONS: Our analysis revealed a remarkable lack of consensus on various aspects of the routine diagnosis and treatment of AD. These findings suggest the presence of unmet needs or limited implementation of guidelines for the management of AD and encourage further research to explore the causes of this low consensus on the management of AD in the real-world setting. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13555-021-00592-y. Springer Healthcare 2021-08-23 /pmc/articles/PMC8484426/ /pubmed/34426957 http://dx.doi.org/10.1007/s13555-021-00592-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Carrascosa, Jose Manuel
de la Cueva, Pablo
de Lucas, Raul
Fonseca, Eduardo
Martín, Ana
Vicente, Asunción
Fortes, Maria Pilar
Gómez, Susana
Rebollo, Francisco José
Patient Journey in Atopic Dermatitis: The Real-World Scenario
title Patient Journey in Atopic Dermatitis: The Real-World Scenario
title_full Patient Journey in Atopic Dermatitis: The Real-World Scenario
title_fullStr Patient Journey in Atopic Dermatitis: The Real-World Scenario
title_full_unstemmed Patient Journey in Atopic Dermatitis: The Real-World Scenario
title_short Patient Journey in Atopic Dermatitis: The Real-World Scenario
title_sort patient journey in atopic dermatitis: the real-world scenario
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484426/
https://www.ncbi.nlm.nih.gov/pubmed/34426957
http://dx.doi.org/10.1007/s13555-021-00592-y
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