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A systems approach to elucidate personalized mechanistic complexities of antibody-Fc receptor activation post-vaccination

Immunoglobulin G (IgG) antibodies that activate Fc-mediated immune functions have been correlated with vaccine efficacy, but it is difficult to unravel the relative roles of multiple IgG and Fc receptor (FcR) features that have the capacity to influence IgG-FcR complex formation but vary on a person...

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Detalles Bibliográficos
Autores principales: Lemke, Melissa M., McLean, Milla R., Lee, Christina Y., Lopez, Ester, Bozich, Emily R., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kratochvil, Sven, Wines, Bruce D., Hogarth, P. Mark, Kent, Stephen J., Chung, Amy W., Arnold, Kelly B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484512/
https://www.ncbi.nlm.nih.gov/pubmed/34622227
http://dx.doi.org/10.1016/j.xcrm.2021.100386

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