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Cortical thickness is differently associated with ALDH2 rs671 polymorphism according to level of amyloid deposition

Accumulating evidence indicates that amyloid-beta (Aβ) deposition and biogenic aldehyde accumulation contribute to the pathogenesis of neurodegenerative diseases. Human aldehyde dehydrogenase 2 (ALDH2) metabolizes biogenic aldehydes produced in the brain to prevent damage. However, r671G>A, a sin...

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Detalles Bibliográficos
Autores principales:	Cho, Yong Hyuk, Lee, Heirim, Kim, Na-Rae, Choi, Jin Wook, Roh, Hyun Woong, Ha, Jae Ho, Hong, Chang Hyung, Seo, Sang Won, Choi, Seong Hye, Kim, Eun-Joo, Kim, Byeong C., Kim, Seong Yoon, Cheong, Jaeyoun, Park, Bumhee, Son, Sang Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484554/ https://www.ncbi.nlm.nih.gov/pubmed/34593890 http://dx.doi.org/10.1038/s41598-021-98834-8

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