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Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia
In recent years, there has been a controversial discussion about whether borderline dysplastic hips should be treated with an arthroscopic procedure or rather with an acetabular reorientation. New research suggests that a classification into stable and unstable hips may be helpful. The aim of the st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484561/ https://www.ncbi.nlm.nih.gov/pubmed/34593957 http://dx.doi.org/10.1038/s41598-021-99011-7 |
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author | Zimmerer, A. Löchel, J. Schoon, J. Janz, V. Wassilew, G. I. |
author_facet | Zimmerer, A. Löchel, J. Schoon, J. Janz, V. Wassilew, G. I. |
author_sort | Zimmerer, A. |
collection | PubMed |
description | In recent years, there has been a controversial discussion about whether borderline dysplastic hips should be treated with an arthroscopic procedure or rather with an acetabular reorientation. New research suggests that a classification into stable and unstable hips may be helpful. The aim of the study was to validate (1) the intra- and interobserver reliability of a newly defined radiographic parameter named the Gothic Arch Angle, (2) the association between the GAA and previously existing measurements used to define severity of acetabular dysplasia, and (3) the correlation between radiographic measurements of acetabular dysplasia with MRI findings previously suggestive of hip instability. We defined and validated the GAA in 10 standardized radiographs of asymptomatic hips by two observers and calculated intra- and interobserver coefficients at two individual dates. Subsequently, a consecutive series of 100 patients with dysplastic hips (LCEA < 25°, Toennis grade ≤ 1) were evaluated for signs of instability on anteroposterior (a.p.) pelvic radiographs and direct MR arthrography and were divided in two groups: stable and unstable. In these patients the LCEA, the AI, the FEAR index and the GAA were radiographically evaluated. Correlation analyses and a logistic regression analysis was performed to identify the predictive value of instability for each radiographic parameter. Cutoff probabilities analysis was performed using standard receiver operating characteristic (ROC) curves to rate the predictive efficiency value of the GAA. The GAA showed excellent inter- and intraobserver reliability. A correlation was found between GAA and FEAR index. A logistic regression analysis showed that LCEA, FEAR index and GAA are distinct predictors of instability in hip dysplasia. The GAA showed the largest area under the curve (AUC 0.96), indicating it to be the best predictor of instability with an optimal cutoff value of 90° (sensitivity, 0.95; specificity, 0.93). The GAA is a new available indicator for instability and is thus suggested to be used as a future radiographic parameter for the stability of dysplastic hips. Further studies are needed to understand how this parameter might additionally predict clinical outcome in the treatment of hip dysplasia. Level of evidence: Level III, diagnostic study. |
format | Online Article Text |
id | pubmed-8484561 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84845612021-10-04 Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia Zimmerer, A. Löchel, J. Schoon, J. Janz, V. Wassilew, G. I. Sci Rep Article In recent years, there has been a controversial discussion about whether borderline dysplastic hips should be treated with an arthroscopic procedure or rather with an acetabular reorientation. New research suggests that a classification into stable and unstable hips may be helpful. The aim of the study was to validate (1) the intra- and interobserver reliability of a newly defined radiographic parameter named the Gothic Arch Angle, (2) the association between the GAA and previously existing measurements used to define severity of acetabular dysplasia, and (3) the correlation between radiographic measurements of acetabular dysplasia with MRI findings previously suggestive of hip instability. We defined and validated the GAA in 10 standardized radiographs of asymptomatic hips by two observers and calculated intra- and interobserver coefficients at two individual dates. Subsequently, a consecutive series of 100 patients with dysplastic hips (LCEA < 25°, Toennis grade ≤ 1) were evaluated for signs of instability on anteroposterior (a.p.) pelvic radiographs and direct MR arthrography and were divided in two groups: stable and unstable. In these patients the LCEA, the AI, the FEAR index and the GAA were radiographically evaluated. Correlation analyses and a logistic regression analysis was performed to identify the predictive value of instability for each radiographic parameter. Cutoff probabilities analysis was performed using standard receiver operating characteristic (ROC) curves to rate the predictive efficiency value of the GAA. The GAA showed excellent inter- and intraobserver reliability. A correlation was found between GAA and FEAR index. A logistic regression analysis showed that LCEA, FEAR index and GAA are distinct predictors of instability in hip dysplasia. The GAA showed the largest area under the curve (AUC 0.96), indicating it to be the best predictor of instability with an optimal cutoff value of 90° (sensitivity, 0.95; specificity, 0.93). The GAA is a new available indicator for instability and is thus suggested to be used as a future radiographic parameter for the stability of dysplastic hips. Further studies are needed to understand how this parameter might additionally predict clinical outcome in the treatment of hip dysplasia. Level of evidence: Level III, diagnostic study. Nature Publishing Group UK 2021-09-30 /pmc/articles/PMC8484561/ /pubmed/34593957 http://dx.doi.org/10.1038/s41598-021-99011-7 Text en © The Author(s) 2021, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Zimmerer, A. Löchel, J. Schoon, J. Janz, V. Wassilew, G. I. Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title | Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title_full | Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title_fullStr | Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title_full_unstemmed | Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title_short | Defining the Gothic Arch Angle (GAA) as a radiographic diagnostic tool for instability in hip dysplasia |
title_sort | defining the gothic arch angle (gaa) as a radiographic diagnostic tool for instability in hip dysplasia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484561/ https://www.ncbi.nlm.nih.gov/pubmed/34593957 http://dx.doi.org/10.1038/s41598-021-99011-7 |
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