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Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition
Uncontrolled mitosis is one of the most important features of cancer, and mitotic kinases are thought to be ideal targets for anticancer therapeutics. However, despite numerous clinical attempts spanning decades, clinical trials for mitotic kinase-targeting agents have generally stalled in the late...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484571/ https://www.ncbi.nlm.nih.gov/pubmed/34593753 http://dx.doi.org/10.1038/s41419-021-04190-w |