Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition

Uncontrolled mitosis is one of the most important features of cancer, and mitotic kinases are thought to be ideal targets for anticancer therapeutics. However, despite numerous clinical attempts spanning decades, clinical trials for mitotic kinase-targeting agents have generally stalled in the late...

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Detalles Bibliográficos
Autores principales: Zhang, Zijian, Zeng, Deshun, Zhang, Wei, Chen, Ailin, Lei, Jie, Liu, Fang, Deng, Bing, Zhuo, Junxiao, He, Bin, Yan, Min, Lei, Xinxing, Wang, Shulan, Lam, Eric W.-F., Liu, Quentin, Wang, Zifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484571/
https://www.ncbi.nlm.nih.gov/pubmed/34593753
http://dx.doi.org/10.1038/s41419-021-04190-w

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