Methylprednisolone stimulated gene expression (GILZ, MCL-1) and basal cortisol levels in multiple sclerosis patients in relapse are associated with clinical response

Glucocorticoids (GCs) are the main treatment of relapse in multiple sclerosis (MS). Decreased sensitivity to GCs in MS patients has been associated with lack of the suppressive effect of GCs on inflammatory molecules as well as increased resistance to apoptosis. We investigated GC-sensitivity by mea...

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Detalles Bibliográficos
Autores principales: Evangelopoulos, Maria Eleftheria, Nasiri-Ansari, Narjes, Kassi, Eva, Papadopoulou, Anna, Evangelopoulos, Dimitrios Stergios, Moutsatsou, Paraskevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484573/
https://www.ncbi.nlm.nih.gov/pubmed/34593869
http://dx.doi.org/10.1038/s41598-021-98868-y

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