Cargando…
WEE1i-ATRi combination therapy: a promising low-dose treatment for CCNE1-amplified gynecologic cancers
CCNE1 amplification is an oncogenic driver for many gynecologic cancers and is associated with poor patient outcomes. In this issue, Xu et al.(1) identify a combination therapy that is responsive to high CCNE1-copy number ovarian and endometrial cancers using PDX models.
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484682/ https://www.ncbi.nlm.nih.gov/pubmed/34622238 http://dx.doi.org/10.1016/j.xcrm.2021.100402 |