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Blocking endogenous IL-6 impairs mobilization of free fatty acids during rest and exercise in lean and obese men

Lack of interleukin-6 (IL-6) leads to expansion of adipose tissue mass in rodents and humans. The exact underlying mechanisms have not been identified. In this placebo-controlled, non-randomized, participant-blinded crossover study, we use the IL-6 receptor antibody tocilizumab to investigate the ro...

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Detalles Bibliográficos
Autores principales: Trinh, Beckey, Peletier, Merel, Simonsen, Casper, Plomgaard, Peter, Karstoft, Kristian, Klarlund Pedersen, Bente, van Hall, Gerrit, Ellingsgaard, Helga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484687/
https://www.ncbi.nlm.nih.gov/pubmed/34622233
http://dx.doi.org/10.1016/j.xcrm.2021.100396

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