Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

Immune suppression by CD4(+)FOXP3(+) regulatory T (Treg) cells and tumor infiltration by CD8(+) effector T cells represent two major factors impacting response to cancer immunotherapy. Using deconvolution-based transcriptional profiling of human papilloma virus (HPV)-negative oral squamous cell carc...

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Detalles Bibliográficos
Autores principales: Chao, Jaime L., Korzinkin, Michael, Zhavoronkov, Alex, Ozerov, Ivan V., Walker, Matthew T., Higgins, Kathleen, Lingen, Mark W., Izumchenko, Evgeny, Savage, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484691/
https://www.ncbi.nlm.nih.gov/pubmed/34622236
http://dx.doi.org/10.1016/j.xcrm.2021.100399

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