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Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning

The interventional treatment of cerebral aneurysm requires hemodynamics to provide proper guidance. Computational fluid dynamics (CFD) is gradually used in calculating cerebral aneurysm hemodynamics before and after flow-diverting (FD) stent placement. However, the complex operation (such as the con...

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Autores principales: Li, Gaoyang, Song, Xiaorui, Wang, Haoran, Liu, Siwei, Ji, Jiayuan, Guo, Yuting, Qiao, Aike, Liu, Youjun, Wang, Xuezheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484706/
https://www.ncbi.nlm.nih.gov/pubmed/34603085
http://dx.doi.org/10.3389/fphys.2021.733444
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author Li, Gaoyang
Song, Xiaorui
Wang, Haoran
Liu, Siwei
Ji, Jiayuan
Guo, Yuting
Qiao, Aike
Liu, Youjun
Wang, Xuezheng
author_facet Li, Gaoyang
Song, Xiaorui
Wang, Haoran
Liu, Siwei
Ji, Jiayuan
Guo, Yuting
Qiao, Aike
Liu, Youjun
Wang, Xuezheng
author_sort Li, Gaoyang
collection PubMed
description The interventional treatment of cerebral aneurysm requires hemodynamics to provide proper guidance. Computational fluid dynamics (CFD) is gradually used in calculating cerebral aneurysm hemodynamics before and after flow-diverting (FD) stent placement. However, the complex operation (such as the construction and placement simulation of fully resolved or porous-medium FD stent) and high computational cost of CFD hinder its application. To solve these problems, we applied aneurysm hemodynamics point cloud data sets and a deep learning network with double input and sampling channels. The flexible point cloud format can represent the geometry and flow distribution of different aneurysms before and after FD stent (represented by porous medium layer) placement with high resolution. The proposed network can directly analyze the relationship between aneurysm geometry and internal hemodynamics, to further realize the flow field prediction and avoid the complex operation of CFD. Statistical analysis shows that the prediction results of hemodynamics by our deep learning method are consistent with the CFD method (error function <13%), but the calculation time is significantly reduced 1,800 times. This study develops a novel deep learning method that can accurately predict the hemodynamics of different cerebral aneurysms before and after FD stent placement with low computational cost and simple operation processes.
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spelling pubmed-84847062021-10-02 Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning Li, Gaoyang Song, Xiaorui Wang, Haoran Liu, Siwei Ji, Jiayuan Guo, Yuting Qiao, Aike Liu, Youjun Wang, Xuezheng Front Physiol Physiology The interventional treatment of cerebral aneurysm requires hemodynamics to provide proper guidance. Computational fluid dynamics (CFD) is gradually used in calculating cerebral aneurysm hemodynamics before and after flow-diverting (FD) stent placement. However, the complex operation (such as the construction and placement simulation of fully resolved or porous-medium FD stent) and high computational cost of CFD hinder its application. To solve these problems, we applied aneurysm hemodynamics point cloud data sets and a deep learning network with double input and sampling channels. The flexible point cloud format can represent the geometry and flow distribution of different aneurysms before and after FD stent (represented by porous medium layer) placement with high resolution. The proposed network can directly analyze the relationship between aneurysm geometry and internal hemodynamics, to further realize the flow field prediction and avoid the complex operation of CFD. Statistical analysis shows that the prediction results of hemodynamics by our deep learning method are consistent with the CFD method (error function <13%), but the calculation time is significantly reduced 1,800 times. This study develops a novel deep learning method that can accurately predict the hemodynamics of different cerebral aneurysms before and after FD stent placement with low computational cost and simple operation processes. Frontiers Media S.A. 2021-09-17 /pmc/articles/PMC8484706/ /pubmed/34603085 http://dx.doi.org/10.3389/fphys.2021.733444 Text en Copyright © 2021 Li, Song, Wang, Liu, Ji, Guo, Qiao, Liu and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Li, Gaoyang
Song, Xiaorui
Wang, Haoran
Liu, Siwei
Ji, Jiayuan
Guo, Yuting
Qiao, Aike
Liu, Youjun
Wang, Xuezheng
Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title_full Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title_fullStr Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title_full_unstemmed Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title_short Prediction of Cerebral Aneurysm Hemodynamics With Porous-Medium Models of Flow-Diverting Stents via Deep Learning
title_sort prediction of cerebral aneurysm hemodynamics with porous-medium models of flow-diverting stents via deep learning
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484706/
https://www.ncbi.nlm.nih.gov/pubmed/34603085
http://dx.doi.org/10.3389/fphys.2021.733444
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