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Tunicamycin Induces Hepatic Stellate Cell Apoptosis Through Calpain-2/Ca(2 +)-Dependent Endoplasmic Reticulum Stress Pathway

It has been reported that calpain/caspase-mediated apoptosis induced by endoplasmic reticulum stress (ERS) in hepatic stellate cells (HSCs) by previous studies. At present, the activation of HSC is an important cause of liver fibrosis, and the induction of HSC apoptosis plays an irreplaceable role i...

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Detalles Bibliográficos
Autores principales: Liu, Haiying, Dai, Linyu, Wang, Ming, Feng, Fumin, Xiao, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484751/
https://www.ncbi.nlm.nih.gov/pubmed/34604209
http://dx.doi.org/10.3389/fcell.2021.684857