Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid

Hibernation is an example of extreme hypometabolic behavior. How mammals achieve such a state of suspended animation remains unclear. Here we show that several strains of type 2 diabetic mice spontaneously enter into hibernation-like suspended animation (HLSA) in cold temperatures. Nondiabetic mice...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Cheng, Rui, Zhao, Yue, Ge, Wenhao, Yang, Yunxia, Ding, Zhao, Xu, Xi, Wang, Zhongqiu, Wu, Zhenguo, Zhang, Jianfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484811/
https://www.ncbi.nlm.nih.gov/pubmed/34487763
http://dx.doi.org/10.1016/j.jbc.2021.101166

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