Melatonin Maintains Anabolic-Catabolic Equilibrium and Regulates Circadian Rhythm During Osteoarthritis Development in Animal Models: A Systematic Review and Meta-analysis

Background: The driving force behind osteoarthritis (OA) pathogenesis is an anabolic-catabolic (a/c) imbalance. Melatonin (MT) is a key player in maintaining a/c stability and mitigates OA pathogenesis, but mechanisms underlying its effects remain poorly understood. Objectives: We performed a system...

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Detalles Bibliográficos
Autores principales: Sumsuzzman, Dewan Md., Choi, Jeonghyun, Khan, Zeeshan Ahmad, Kamenos, George, Hong, Yonggeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484877/
https://www.ncbi.nlm.nih.gov/pubmed/34603028
http://dx.doi.org/10.3389/fphar.2021.714974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484877/
https://www.ncbi.nlm.nih.gov/pubmed/34603028
http://dx.doi.org/10.3389/fphar.2021.714974

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