Cargando…
Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484948/ https://www.ncbi.nlm.nih.gov/pubmed/34621959 http://dx.doi.org/10.1016/j.ijwd.2021.02.002 |
_version_ | 1784577433378226176 |
---|---|
author | Saqib, Najam U Bhat, Yasmeen Jabeen Shah, Iffat Hassan Haq, Inaam Devi, Reeta Shah, Aaqib Aslam Shah, Faizan Younis |
author_facet | Saqib, Najam U Bhat, Yasmeen Jabeen Shah, Iffat Hassan Haq, Inaam Devi, Reeta Shah, Aaqib Aslam Shah, Faizan Younis |
author_sort | Saqib, Najam U |
collection | PubMed |
description | BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis clinical findings, and the validity of trichoscopy in cases with a doubtful clinical diagnosis. METHODS: A hospital-based observational, cross-sectional study was carried out on female patients with alopecia. A trichoscopic diagnosis was made and correlated with a clinical diagnosis. The validity of trichoscopy in doubtful cases was evaluated by reporting the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic value. RESULTS: On trichoscopy, increased hair diameter diversity > 20%, single-hair follicular unit, vellus hair, peripilar sign, and focal atrichia were commonly seen in female pattern hair loss. In telogen effluvium, there was a scarceness of specific findings. In cicatricial alopecias, loss of follicular ostia, erythema, white macules, blue-gray dots, white dots, tufted hair, and keratotic follicular plugging were observed. A good agreement between trichoscopy and clinical diagnosis was found (Cohen’s Kappa = 0.824; 95% confidence interval, 0.756–0.892). The validity of trichoscopy in doubtful cases was evaluated using the validity parameters, which were high in all alopecias. LIMITATIONS: Histopathology testing was not done in all patients. CONCLUSION: Trichoscopy helped reach a definitive diagnosis in patients in whom the clinical diagnosis was doubtful. Thus, trichoscopy is a sensitive and specific investigation that can be valuable in women with alopecia. |
format | Online Article Text |
id | pubmed-8484948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-84849482021-10-06 Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women Saqib, Najam U Bhat, Yasmeen Jabeen Shah, Iffat Hassan Haq, Inaam Devi, Reeta Shah, Aaqib Aslam Shah, Faizan Younis Int J Womens Dermatol Original Research BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis clinical findings, and the validity of trichoscopy in cases with a doubtful clinical diagnosis. METHODS: A hospital-based observational, cross-sectional study was carried out on female patients with alopecia. A trichoscopic diagnosis was made and correlated with a clinical diagnosis. The validity of trichoscopy in doubtful cases was evaluated by reporting the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic value. RESULTS: On trichoscopy, increased hair diameter diversity > 20%, single-hair follicular unit, vellus hair, peripilar sign, and focal atrichia were commonly seen in female pattern hair loss. In telogen effluvium, there was a scarceness of specific findings. In cicatricial alopecias, loss of follicular ostia, erythema, white macules, blue-gray dots, white dots, tufted hair, and keratotic follicular plugging were observed. A good agreement between trichoscopy and clinical diagnosis was found (Cohen’s Kappa = 0.824; 95% confidence interval, 0.756–0.892). The validity of trichoscopy in doubtful cases was evaluated using the validity parameters, which were high in all alopecias. LIMITATIONS: Histopathology testing was not done in all patients. CONCLUSION: Trichoscopy helped reach a definitive diagnosis in patients in whom the clinical diagnosis was doubtful. Thus, trichoscopy is a sensitive and specific investigation that can be valuable in women with alopecia. Elsevier 2021-02-16 /pmc/articles/PMC8484948/ /pubmed/34621959 http://dx.doi.org/10.1016/j.ijwd.2021.02.002 Text en © 2021 Published by Elsevier Inc. on behalf of Women's Dermatologic Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Research Saqib, Najam U Bhat, Yasmeen Jabeen Shah, Iffat Hassan Haq, Inaam Devi, Reeta Shah, Aaqib Aslam Shah, Faizan Younis Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title | Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title_full | Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title_fullStr | Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title_full_unstemmed | Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title_short | Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
title_sort | assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484948/ https://www.ncbi.nlm.nih.gov/pubmed/34621959 http://dx.doi.org/10.1016/j.ijwd.2021.02.002 |
work_keys_str_mv | AT saqibnajamu assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT bhatyasmeenjabeen assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT shahiffathassan assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT haqinaam assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT devireeta assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT shahaaqibaslam assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen AT shahfaizanyounis assessmentreliabilityandvalidityoftrichoscopyintheevaluationofalopeciainwomen |