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Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women

BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis...

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Autores principales: Saqib, Najam U, Bhat, Yasmeen Jabeen, Shah, Iffat Hassan, Haq, Inaam, Devi, Reeta, Shah, Aaqib Aslam, Shah, Faizan Younis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484948/
https://www.ncbi.nlm.nih.gov/pubmed/34621959
http://dx.doi.org/10.1016/j.ijwd.2021.02.002
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author Saqib, Najam U
Bhat, Yasmeen Jabeen
Shah, Iffat Hassan
Haq, Inaam
Devi, Reeta
Shah, Aaqib Aslam
Shah, Faizan Younis
author_facet Saqib, Najam U
Bhat, Yasmeen Jabeen
Shah, Iffat Hassan
Haq, Inaam
Devi, Reeta
Shah, Aaqib Aslam
Shah, Faizan Younis
author_sort Saqib, Najam U
collection PubMed
description BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis clinical findings, and the validity of trichoscopy in cases with a doubtful clinical diagnosis. METHODS: A hospital-based observational, cross-sectional study was carried out on female patients with alopecia. A trichoscopic diagnosis was made and correlated with a clinical diagnosis. The validity of trichoscopy in doubtful cases was evaluated by reporting the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic value. RESULTS: On trichoscopy, increased hair diameter diversity > 20%, single-hair follicular unit, vellus hair, peripilar sign, and focal atrichia were commonly seen in female pattern hair loss. In telogen effluvium, there was a scarceness of specific findings. In cicatricial alopecias, loss of follicular ostia, erythema, white macules, blue-gray dots, white dots, tufted hair, and keratotic follicular plugging were observed. A good agreement between trichoscopy and clinical diagnosis was found (Cohen’s Kappa = 0.824; 95% confidence interval, 0.756–0.892). The validity of trichoscopy in doubtful cases was evaluated using the validity parameters, which were high in all alopecias. LIMITATIONS: Histopathology testing was not done in all patients. CONCLUSION: Trichoscopy helped reach a definitive diagnosis in patients in whom the clinical diagnosis was doubtful. Thus, trichoscopy is a sensitive and specific investigation that can be valuable in women with alopecia.
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spelling pubmed-84849482021-10-06 Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women Saqib, Najam U Bhat, Yasmeen Jabeen Shah, Iffat Hassan Haq, Inaam Devi, Reeta Shah, Aaqib Aslam Shah, Faizan Younis Int J Womens Dermatol Original Research BACKGROUND: Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. OBJECTIVE: The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis clinical findings, and the validity of trichoscopy in cases with a doubtful clinical diagnosis. METHODS: A hospital-based observational, cross-sectional study was carried out on female patients with alopecia. A trichoscopic diagnosis was made and correlated with a clinical diagnosis. The validity of trichoscopy in doubtful cases was evaluated by reporting the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic value. RESULTS: On trichoscopy, increased hair diameter diversity > 20%, single-hair follicular unit, vellus hair, peripilar sign, and focal atrichia were commonly seen in female pattern hair loss. In telogen effluvium, there was a scarceness of specific findings. In cicatricial alopecias, loss of follicular ostia, erythema, white macules, blue-gray dots, white dots, tufted hair, and keratotic follicular plugging were observed. A good agreement between trichoscopy and clinical diagnosis was found (Cohen’s Kappa = 0.824; 95% confidence interval, 0.756–0.892). The validity of trichoscopy in doubtful cases was evaluated using the validity parameters, which were high in all alopecias. LIMITATIONS: Histopathology testing was not done in all patients. CONCLUSION: Trichoscopy helped reach a definitive diagnosis in patients in whom the clinical diagnosis was doubtful. Thus, trichoscopy is a sensitive and specific investigation that can be valuable in women with alopecia. Elsevier 2021-02-16 /pmc/articles/PMC8484948/ /pubmed/34621959 http://dx.doi.org/10.1016/j.ijwd.2021.02.002 Text en © 2021 Published by Elsevier Inc. on behalf of Women's Dermatologic Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Saqib, Najam U
Bhat, Yasmeen Jabeen
Shah, Iffat Hassan
Haq, Inaam
Devi, Reeta
Shah, Aaqib Aslam
Shah, Faizan Younis
Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title_full Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title_fullStr Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title_full_unstemmed Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title_short Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
title_sort assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484948/
https://www.ncbi.nlm.nih.gov/pubmed/34621959
http://dx.doi.org/10.1016/j.ijwd.2021.02.002
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