Cargando…

Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women

Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods For...

Descripción completa

Detalles Bibliográficos
Autores principales: Akın, Tezcan, Birben, Birkan, Akkurt, Gökhan, Karaca, Onur, Dönmez, Mustafa, Er, Sadettin, Tez, Mesut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484999/
https://www.ncbi.nlm.nih.gov/pubmed/34646676
http://dx.doi.org/10.7759/cureus.17627
_version_ 1784577446955188224
author Akın, Tezcan
Birben, Birkan
Akkurt, Gökhan
Karaca, Onur
Dönmez, Mustafa
Er, Sadettin
Tez, Mesut
author_facet Akın, Tezcan
Birben, Birkan
Akkurt, Gökhan
Karaca, Onur
Dönmez, Mustafa
Er, Sadettin
Tez, Mesut
author_sort Akın, Tezcan
collection PubMed
description Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods Forty-two patients who underwent appendectomy during pregnancy were evaluated. The demographic characteristics, laboratory parameters and imaging methods of the patients were examined. According to the pathology results, the patients were evaluated in two groups as normal appendix and acute appendicitis. In addition, a non-pregnant control group was formed to compare the results between the pregnant and control groups. Results The mean age of the 42 patients was 30±6 years, and the pathology results were evaluated as normal in 16 (38.1%) of the patients. As imaging methods, ultrasonography was undertaken in all patients, with MRI being additionally performed in two patients. When the normal appendix and acute appendicitis groups were compared, no significant difference was observed in terms of laboratory parameters (neutrophil, lymphocyte, white blood cell and platelet counts, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, mean thrombocyte volume, red cell distribution width, and pregnancy trimesters (P>0.05). The group that had undergone appendectomy had a significantly higher rate of negative appendectomy compared to the control group (P=0.001). Conclusion Laboratory parameters alone cannot be sufficient for the diagnosis of acute appendicitis in pregnant patients. If clinical examination, laboratory parameters and USG are not sufficient for diagnosis, MRI is the imaging method that should be considered to reduce negative appendectomy rate.
format Online
Article
Text
id pubmed-8484999
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-84849992021-10-12 Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women Akın, Tezcan Birben, Birkan Akkurt, Gökhan Karaca, Onur Dönmez, Mustafa Er, Sadettin Tez, Mesut Cureus Obstetrics/Gynecology Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods Forty-two patients who underwent appendectomy during pregnancy were evaluated. The demographic characteristics, laboratory parameters and imaging methods of the patients were examined. According to the pathology results, the patients were evaluated in two groups as normal appendix and acute appendicitis. In addition, a non-pregnant control group was formed to compare the results between the pregnant and control groups. Results The mean age of the 42 patients was 30±6 years, and the pathology results were evaluated as normal in 16 (38.1%) of the patients. As imaging methods, ultrasonography was undertaken in all patients, with MRI being additionally performed in two patients. When the normal appendix and acute appendicitis groups were compared, no significant difference was observed in terms of laboratory parameters (neutrophil, lymphocyte, white blood cell and platelet counts, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, mean thrombocyte volume, red cell distribution width, and pregnancy trimesters (P>0.05). The group that had undergone appendectomy had a significantly higher rate of negative appendectomy compared to the control group (P=0.001). Conclusion Laboratory parameters alone cannot be sufficient for the diagnosis of acute appendicitis in pregnant patients. If clinical examination, laboratory parameters and USG are not sufficient for diagnosis, MRI is the imaging method that should be considered to reduce negative appendectomy rate. Cureus 2021-08-31 /pmc/articles/PMC8484999/ /pubmed/34646676 http://dx.doi.org/10.7759/cureus.17627 Text en Copyright © 2021, Akın et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Akın, Tezcan
Birben, Birkan
Akkurt, Gökhan
Karaca, Onur
Dönmez, Mustafa
Er, Sadettin
Tez, Mesut
Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title_full Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title_fullStr Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title_full_unstemmed Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title_short Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
title_sort acute appendicitis during pregnancy: a case series of 42 pregnant women
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484999/
https://www.ncbi.nlm.nih.gov/pubmed/34646676
http://dx.doi.org/10.7759/cureus.17627
work_keys_str_mv AT akıntezcan acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT birbenbirkan acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT akkurtgokhan acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT karacaonur acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT donmezmustafa acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT ersadettin acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen
AT tezmesut acuteappendicitisduringpregnancyacaseseriesof42pregnantwomen