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Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women
Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods For...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484999/ https://www.ncbi.nlm.nih.gov/pubmed/34646676 http://dx.doi.org/10.7759/cureus.17627 |
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author | Akın, Tezcan Birben, Birkan Akkurt, Gökhan Karaca, Onur Dönmez, Mustafa Er, Sadettin Tez, Mesut |
author_facet | Akın, Tezcan Birben, Birkan Akkurt, Gökhan Karaca, Onur Dönmez, Mustafa Er, Sadettin Tez, Mesut |
author_sort | Akın, Tezcan |
collection | PubMed |
description | Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods Forty-two patients who underwent appendectomy during pregnancy were evaluated. The demographic characteristics, laboratory parameters and imaging methods of the patients were examined. According to the pathology results, the patients were evaluated in two groups as normal appendix and acute appendicitis. In addition, a non-pregnant control group was formed to compare the results between the pregnant and control groups. Results The mean age of the 42 patients was 30±6 years, and the pathology results were evaluated as normal in 16 (38.1%) of the patients. As imaging methods, ultrasonography was undertaken in all patients, with MRI being additionally performed in two patients. When the normal appendix and acute appendicitis groups were compared, no significant difference was observed in terms of laboratory parameters (neutrophil, lymphocyte, white blood cell and platelet counts, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, mean thrombocyte volume, red cell distribution width, and pregnancy trimesters (P>0.05). The group that had undergone appendectomy had a significantly higher rate of negative appendectomy compared to the control group (P=0.001). Conclusion Laboratory parameters alone cannot be sufficient for the diagnosis of acute appendicitis in pregnant patients. If clinical examination, laboratory parameters and USG are not sufficient for diagnosis, MRI is the imaging method that should be considered to reduce negative appendectomy rate. |
format | Online Article Text |
id | pubmed-8484999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-84849992021-10-12 Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women Akın, Tezcan Birben, Birkan Akkurt, Gökhan Karaca, Onur Dönmez, Mustafa Er, Sadettin Tez, Mesut Cureus Obstetrics/Gynecology Introduction It is difficult to diagnose the symptoms of acute appendicitis in pregnant women due to its similarities with pregnancy physiology. In this study, we examined the diagnostic value of laboratory parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods Forty-two patients who underwent appendectomy during pregnancy were evaluated. The demographic characteristics, laboratory parameters and imaging methods of the patients were examined. According to the pathology results, the patients were evaluated in two groups as normal appendix and acute appendicitis. In addition, a non-pregnant control group was formed to compare the results between the pregnant and control groups. Results The mean age of the 42 patients was 30±6 years, and the pathology results were evaluated as normal in 16 (38.1%) of the patients. As imaging methods, ultrasonography was undertaken in all patients, with MRI being additionally performed in two patients. When the normal appendix and acute appendicitis groups were compared, no significant difference was observed in terms of laboratory parameters (neutrophil, lymphocyte, white blood cell and platelet counts, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, mean thrombocyte volume, red cell distribution width, and pregnancy trimesters (P>0.05). The group that had undergone appendectomy had a significantly higher rate of negative appendectomy compared to the control group (P=0.001). Conclusion Laboratory parameters alone cannot be sufficient for the diagnosis of acute appendicitis in pregnant patients. If clinical examination, laboratory parameters and USG are not sufficient for diagnosis, MRI is the imaging method that should be considered to reduce negative appendectomy rate. Cureus 2021-08-31 /pmc/articles/PMC8484999/ /pubmed/34646676 http://dx.doi.org/10.7759/cureus.17627 Text en Copyright © 2021, Akın et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Obstetrics/Gynecology Akın, Tezcan Birben, Birkan Akkurt, Gökhan Karaca, Onur Dönmez, Mustafa Er, Sadettin Tez, Mesut Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title | Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title_full | Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title_fullStr | Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title_full_unstemmed | Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title_short | Acute Appendicitis During Pregnancy: A Case Series of 42 Pregnant Women |
title_sort | acute appendicitis during pregnancy: a case series of 42 pregnant women |
topic | Obstetrics/Gynecology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484999/ https://www.ncbi.nlm.nih.gov/pubmed/34646676 http://dx.doi.org/10.7759/cureus.17627 |
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