A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program

Genotype-phenotype association studies often combine phenotype data from multiple studies to increase statistical power. Harmonization of the data usually requires substantial effort due to heterogeneity in phenotype definitions, study design, data collection procedures, and data-set organization. H...

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Autores principales: Stilp, Adrienne M, Emery, Leslie S, Broome, Jai G, Buth, Erin J, Khan, Alyna T, Laurie, Cecelia A, Wang, Fei Fei, Wong, Quenna, Chen, Dongquan, D’Augustine, Catherine M, Heard-Costa, Nancy L, Hohensee, Chancellor R, Johnson, William Craig, Juarez, Lucia D, Liu, Jingmin, Mutalik, Karen M, Raffield, Laura M, Wiggins, Kerri L, de Vries, Paul S, Kelly, Tanika N, Kooperberg, Charles, Natarajan, Pradeep, Peloso, Gina M, Peyser, Patricia A, Reiner, Alex P, Arnett, Donna K, Aslibekyan, Stella, Barnes, Kathleen C, Bielak, Lawrence F, Bis, Joshua C, Cade, Brian E, Chen, Ming-Huei, Correa, Adolfo, Cupples, L Adrienne, de Andrade, Mariza, Ellinor, Patrick T, Fornage, Myriam, Franceschini, Nora, Gan, Weiniu, Ganesh, Santhi K, Graffelman, Jan, Grove, Megan L, Guo, Xiuqing, Hawley, Nicola L, Hsu, Wan-Ling, Jackson, Rebecca D, Jaquish, Cashell E, Johnson, Andrew D, Kardia, Sharon L R, Kelly, Shannon, Lee, Jiwon, Mathias, Rasika A, McGarvey, Stephen T, Mitchell, Braxton D, Montasser, May E, Morrison, Alanna C, North, Kari E, Nouraie, Seyed Mehdi, Oelsner, Elizabeth C, Pankratz, Nathan, Rich, Stephen S, Rotter, Jerome I, Smith, Jennifer A, Taylor, Kent D, Vasan, Ramachandran S, Weeks, Daniel E, Weiss, Scott T, Wilson, Carla G, Yanek, Lisa R, Psaty, Bruce M, Heckbert, Susan R, Laurie, Cathy C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Study Design
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485147/
https://www.ncbi.nlm.nih.gov/pubmed/33861317
http://dx.doi.org/10.1093/aje/kwab115

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