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Combinatorial molecule screening identified a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells

Combination treatment has proven effective for patients with acute promyelocytic leukemia, exemplifying the importance of therapy targeting multiple components of oncogenic regulation for a successful outcome. However, recent studies have shown that the mutational complexity of acute myeloid leukemi...

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Detalles Bibliográficos
Autores principales:	Hultmark, Simon, Baudet, Aurélie, Schmiderer, Ludwig, Prabhala, Pavan, Palma-Tortosa, Sara, Sandén, Carl, Fioretos, Thoas, Sasidharan, Rajkumar, Larsson, Christer, Lehmann, Sören, Juliusson, Gunnar, Ek, Fredrik, Magnusson, Mattias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485661/ https://www.ncbi.nlm.nih.gov/pubmed/32855276 http://dx.doi.org/10.3324/haematol.2020.249177

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