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Inducible deletion of CDK4 and CDK6 – deciphering CDK4/6 inhibitor effects in the hematopoietic system
Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors are considered a breakthrough in cancer therapy. Currently approved for breast cancer treatment, CDK4/6 inhibitors are extensively tested in other cancer subtypes. Frequently observed side effects include hematological abnormalities such as reduce...
Autores principales: | Maurer, Barbara, Brandstoetter, Tania, Kollmann, Sebastian, Sexl, Veronika, Prchal-Murphy, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485667/ https://www.ncbi.nlm.nih.gov/pubmed/32855282 http://dx.doi.org/10.3324/haematol.2020.256313 |
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