The Mechanism and Consequences of SARS-CoV-2 Spike-Mediated Fusion and Syncytia Formation

Syncytia are formed when individual cells fuse. SARS-CoV-2 induces syncytia when the viral spike (S) protein on the surface of an infected cell interacts with receptors on neighboring cells. Syncytia may potentially contribute to pathology by facilitating viral dissemination, cytopathicity, immune e...

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Detalles Bibliográficos
Autores principales: Rajah, Maaran Michael, Bernier, Annie, Buchrieser, Julian, Schwartz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485708/
https://www.ncbi.nlm.nih.gov/pubmed/34606831
http://dx.doi.org/10.1016/j.jmb.2021.167280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485708/
https://www.ncbi.nlm.nih.gov/pubmed/34606831
http://dx.doi.org/10.1016/j.jmb.2021.167280

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