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The Mechanism and Consequences of SARS-CoV-2 Spike-Mediated Fusion and Syncytia Formation
Syncytia are formed when individual cells fuse. SARS-CoV-2 induces syncytia when the viral spike (S) protein on the surface of an infected cell interacts with receptors on neighboring cells. Syncytia may potentially contribute to pathology by facilitating viral dissemination, cytopathicity, immune e...
Autores principales: | Rajah, Maaran Michael, Bernier, Annie, Buchrieser, Julian, Schwartz, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485708/ https://www.ncbi.nlm.nih.gov/pubmed/34606831 http://dx.doi.org/10.1016/j.jmb.2021.167280 |
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