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Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation

BACKGROUND: Acute pulmonary vein reconnection (PVR) is associated with long procedure times and large radiofrequency (RF) energy delivery during pulmonary vein isolation (PVI). Although the efficacy of high‐power PVI (HP‐PVI) has been recently established, the determinants of acute PVR following HP‐...

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Autores principales: Yazaki, Kyoichiro, Ejima, Koichiro, Kataoka, Shohei, Kanai, Miwa, Higuchi, Satoshi, Yagishita, Daigo, Shoda, Morio, Hagiwara, Nobuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485794/
https://www.ncbi.nlm.nih.gov/pubmed/34621424
http://dx.doi.org/10.1002/joa3.12597
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author Yazaki, Kyoichiro
Ejima, Koichiro
Kataoka, Shohei
Kanai, Miwa
Higuchi, Satoshi
Yagishita, Daigo
Shoda, Morio
Hagiwara, Nobuhisa
author_facet Yazaki, Kyoichiro
Ejima, Koichiro
Kataoka, Shohei
Kanai, Miwa
Higuchi, Satoshi
Yagishita, Daigo
Shoda, Morio
Hagiwara, Nobuhisa
author_sort Yazaki, Kyoichiro
collection PubMed
description BACKGROUND: Acute pulmonary vein reconnection (PVR) is associated with long procedure times and large radiofrequency (RF) energy delivery during pulmonary vein isolation (PVI). Although the efficacy of high‐power PVI (HP‐PVI) has been recently established, the determinants of acute PVR following HP‐PVI remain unclear. METHODS: We evaluated data on 62 patients with paroxysmal atrial fibrillation undergoing unipolar signal modification (USM)‐guided HP‐PVI. A 50‐W RF wave was applied for 3‐5 seconds after USM. In the segments adjacent to the esophagus (SAEs), the RF time was limited to 5 seconds. Each circle was subdivided into six regions (segments), and the possible predictors of acute PVR, including minimum contact force (CF(min)), minimum force‐time integral (FTI(min)), minimum ablation index (AI(min)), minimum impedance drop (Imp‐min), and maximum inter‐lesion distance (ILD(max)), were assessed in each segment. RESULTS: We investigated 1162 ablations in 744 segments (including 124 SAEs). Acute PVR was observed in 21 (17%) SAEs and 43 (7%) other segments (P = .001). The acute PVR segments were characterized by significantly lower CF(min), FTI(min), AI(min), and Imp‐min values in the segments other than the SAEs and larger ILD(max) values in the SAEs. Furthermore, lower Imp‐min and larger ILD(max) values independently predicted acute PVR in the segments other than the SAEs and SAEs (odds ratios 0.90 and 1.39 respectively). Acute PVR was not significantly associated with late atrial fibrillation recurrence. CONCLUSIONS: Avoiding PVR remains a challenge in HP‐PVI cases, but it might be resolved by setting the optimal target impedance drop and lesion distance values.
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spelling pubmed-84857942021-10-06 Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation Yazaki, Kyoichiro Ejima, Koichiro Kataoka, Shohei Kanai, Miwa Higuchi, Satoshi Yagishita, Daigo Shoda, Morio Hagiwara, Nobuhisa J Arrhythm Original Articles BACKGROUND: Acute pulmonary vein reconnection (PVR) is associated with long procedure times and large radiofrequency (RF) energy delivery during pulmonary vein isolation (PVI). Although the efficacy of high‐power PVI (HP‐PVI) has been recently established, the determinants of acute PVR following HP‐PVI remain unclear. METHODS: We evaluated data on 62 patients with paroxysmal atrial fibrillation undergoing unipolar signal modification (USM)‐guided HP‐PVI. A 50‐W RF wave was applied for 3‐5 seconds after USM. In the segments adjacent to the esophagus (SAEs), the RF time was limited to 5 seconds. Each circle was subdivided into six regions (segments), and the possible predictors of acute PVR, including minimum contact force (CF(min)), minimum force‐time integral (FTI(min)), minimum ablation index (AI(min)), minimum impedance drop (Imp‐min), and maximum inter‐lesion distance (ILD(max)), were assessed in each segment. RESULTS: We investigated 1162 ablations in 744 segments (including 124 SAEs). Acute PVR was observed in 21 (17%) SAEs and 43 (7%) other segments (P = .001). The acute PVR segments were characterized by significantly lower CF(min), FTI(min), AI(min), and Imp‐min values in the segments other than the SAEs and larger ILD(max) values in the SAEs. Furthermore, lower Imp‐min and larger ILD(max) values independently predicted acute PVR in the segments other than the SAEs and SAEs (odds ratios 0.90 and 1.39 respectively). Acute PVR was not significantly associated with late atrial fibrillation recurrence. CONCLUSIONS: Avoiding PVR remains a challenge in HP‐PVI cases, but it might be resolved by setting the optimal target impedance drop and lesion distance values. John Wiley and Sons Inc. 2021-07-23 /pmc/articles/PMC8485794/ /pubmed/34621424 http://dx.doi.org/10.1002/joa3.12597 Text en © 2021 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Yazaki, Kyoichiro
Ejima, Koichiro
Kataoka, Shohei
Kanai, Miwa
Higuchi, Satoshi
Yagishita, Daigo
Shoda, Morio
Hagiwara, Nobuhisa
Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title_full Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title_fullStr Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title_full_unstemmed Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title_short Regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
title_sort regional differences in the predictors of acute electrical reconnection following high‐power pulmonary vein isolation for paroxysmal atrial fibrillation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485794/
https://www.ncbi.nlm.nih.gov/pubmed/34621424
http://dx.doi.org/10.1002/joa3.12597
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