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Contribution of HCN1 variant to sinus bradycardia: A case report

BACKGROUND: Missense mutations in the hyperpolarization‐activated cyclic nucleotide‐modulated (HCN) channel 4 (HCN4) are one of the genetic causes of cardiac sinus bradycardia. OBJECTIVE: To investigate possible HCN4 channel mutation in a young patient with profound sinus bradycardia. METHODS: Direc...

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Detalles Bibliográficos
Autores principales: Yu, Hangang, Gall, Bryan, Newman, Mackenzie, Hathaway, Quincy, Brundage, Kathleen, Ammer, Amanda, Mathers, Peter, Siderovski, David, Hull, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485797/
https://www.ncbi.nlm.nih.gov/pubmed/34621433
http://dx.doi.org/10.1002/joa3.12598