Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant

Complications of cirrhosis and portal hypertension (PH) can be reduced by statin therapy. The common loss‐of‐function variant p.V174A in the solute carrier organic anion transporter gene 1B1 (SLCO1B1) gene encoding the organic anion transporting polypeptide 1B1 results in decreased hepatic uptake of...

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Detalles Bibliográficos
Autores principales: Merkel, Melissa, Schneider, Christina, Greinert, Robin, Zipprich, Alexander, Ripoll, Cristina, Lammert, Frank, Reichert, Matthias C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485882/
https://www.ncbi.nlm.nih.gov/pubmed/34558822
http://dx.doi.org/10.1002/hep4.1753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485882/
https://www.ncbi.nlm.nih.gov/pubmed/34558822
http://dx.doi.org/10.1002/hep4.1753

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