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A Systematic Review of the Tumor-Infiltrating CD8(+) T-Cells/PD-L1 Axis in High-Grade Glial Tumors: Toward Personalized Immuno-Oncology

Based on preclinical findings, programmed death-ligand 1 (PD-L1) can substantially attenuate CD8(+) T-cell-mediated anti-tumoral immune responses. However, clinical studies have reported controversial results regarding the significance of the tumor-infiltrating CD8(+) T-cells/PD-L1 axis on the clini...

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Detalles Bibliográficos
Autores principales:	Shadbad, Mahdi Abdoli, Asadzadeh, Zahra, Hosseinkhani, Negar, Derakhshani, Afshin, Alizadeh, Nazila, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486082/ https://www.ncbi.nlm.nih.gov/pubmed/34603316 http://dx.doi.org/10.3389/fimmu.2021.734956

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