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Orally Active Peptide Vector Allows Using Cannabis to Fight Pain While Avoiding Side Effects
[Image: see text] The activation of cannabinoid CB(1) receptors (CB(1)R) by Δ(9)-tetrahydrocannabinol (THC), the main component of Cannabis sativa, induces analgesia. CB(1)R activation, however, also causes cognitive impairment via the serotonin 5HT(2A) receptor (5HT(2A)R), a component of a CB(1)R–5...
Autores principales: | Gallo, Maria, Moreno, Estefanía, Defaus, Sira, Ortega-Alvaro, Antonio, Gonzalez, Angel, Robledo, Patricia, Cavaco, Marco, Neves, Vera, Castanho, Miguel A. R. B., Casadó, Vicent, Pardo, Leonardo, Maldonado, Rafael, Andreu, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486167/ https://www.ncbi.nlm.nih.gov/pubmed/33887904 http://dx.doi.org/10.1021/acs.jmedchem.1c00484 |
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