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Role of BCLAF‐1 in PD‐L1 stabilization in response to ionizing irradiation

Programmed cell death ligand 1 (PD‐L1) is a major immunosuppressive checkpoint protein expressed by tumor cells to subvert anticancer immunity. Recent studies have shown that ionizing radiation (IR) upregulates the expression of PD‐L1 in tumor cells. However, whether an IR‐induced DNA damage respons...

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Detalles Bibliográficos
Autores principales: Ma, Zhao, Wang, Han, Meng, Fanbiao, Han, Yamei, Chen, Yefei, Xiao, Mingming, Jiang, Hongjing, Yu, Zhentao, Xu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486183/
https://www.ncbi.nlm.nih.gov/pubmed/34251713
http://dx.doi.org/10.1111/cas.15056