Cargando…
TH1902, a new docetaxel‐peptide conjugate for the treatment of sortilin‐positive triple‐negative breast cancer
Triple‐negative breast cancer (TNBC) is a heterogeneous subgroup of cancers which lacks the expression and/or amplification of targetable biomarkers (ie, estrogen receptor, progestrogen receptor, and human epidermal growth factor receptor 2), and is often associated with the worse disease‐specific o...
Autores principales: | Demeule, Michel, Charfi, Cyndia, Currie, Jean‐Christophe, Larocque, Alain, Zgheib, Alain, Kozelko, Sophie, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486219/ https://www.ncbi.nlm.nih.gov/pubmed/34314556 http://dx.doi.org/10.1111/cas.15086 |
Ejemplares similares
-
The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers
por: Currie, Jean-Christophe, et al.
Publicado: (2022) -
The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells
por: Demeule, Michel, et al.
Publicado: (2022) -
New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells
por: Charfi, Cyndia, et al.
Publicado: (2021) -
A Role for the Cavin-3/Matrix Metalloproteinase-9 Signaling Axis in the Regulation of PMA-Activated Human HT1080 Fibrosarcoma Cell Neoplastic Phenotype
por: Toufaily, Chirine, et al.
Publicado: (2014) -
Cavin-2 Functions as a Suppressive Regulator in TNF-induced Mesenchymal Stromal Cell Inflammation and Angiogenic Phenotypes
por: Annabi, Bayader, et al.
Publicado: (2017)