Cargando…

The Synergistic Effects of Astragalus mongholicus and Salvia miltiorrhiza on Coronary Heart Disease Identified by Network Pharmacology and Experiment

BACKGROUND AND PURPOSE: Two Chinese herbal medicines Huang Qi (HQ, Astragalus mongholicus) and Dan Shen (DS, Salvia miltiorrhiza) are often combined to treat coronary heart disease (CHD). The purpose of this study was to identify the underlying synergistic effects and mechanisms of HQ and DS against...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yun, Wang, Jie, Liu, Yong-Mei, Chen, Yin-Ying, Yang, Xiao-Chen, Duan, Lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486279/ https://www.ncbi.nlm.nih.gov/pubmed/34611395 http://dx.doi.org/10.2147/DDDT.S326024

Ejemplares similares

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza
por: Jiang, Zhouqian, et al.
Publicado: (2019)

Astragalus Mongholicus: A review of its anti-fibrosis properties
por: Gong, Fengying, et al.
Publicado: (2022)

Effects of Salvia miltiorrhiza extract on lung adenocarcinoma
por: Tian, Huixiang, et al.
Publicado: (2021)

Hyperspectral imaging with machine learning for non-destructive classification of Astragalus membranaceus var. mongholicus, Astragalus membranaceus, and similar seeds
por: Xu, Yanan, et al.
Publicado: (2022)

Study on the Antihypertensive Mechanism of Astragalus membranaceus and Salvia miltiorrhiza Based on Intestinal Flora-Host Metabolism
por: Han, Cong, et al.
Publicado: (2019)

Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction
por: Lin, Tsai-Hui, et al.
Publicado: (2010)

Chemical and genetic diversity of Astragalus mongholicus grown in different eco-climatic regions
por: Li, Lin, et al.
Publicado: (2017)

Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification
por: Fu, Lili, et al.
Publicado: (2022)

Effects of Astragalus injection and Salvia Miltiorrhiza injection on serum inflammatory markers in patients with stable coronary heart disease: a randomized controlled trial protocol
por: Luo, Zhihao, et al.
Publicado: (2020)

A network pharmacology approach to reveal the protective mechanism of Salvia miltiorrhiza-Dalbergia odorifera coupled-herbs on coronary heart disease
por: Li, Fei, et al.
Publicado: (2019)

Comparative analysis of twenty-five compounds in different parts of Astragalus membranaceus var. mongholicus and Astragalus membranaceus by UPLC-MS/MS
por: Li, Yuan, et al.
Publicado: (2019)

WTAP mediates the anti-inflammatory effect of Astragalus mongholicus polysaccharide on THP-1 macrophages
por: Long, Haijiao, et al.
Publicado: (2022)

The Composition of Root-Associated Bacteria and Fungi of Astragalus mongholicus and Their Relationship With the Bioactive Ingredients
por: Li, Yanmei, et al.
Publicado: (2021)

A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae
por: Luo, Yi, et al.
Publicado: (2019)

Distinguishing Astragalus mongholicus and Its Planting Soil Samples from Different Regions by ICP-AES
por: Li, Lin, et al.
Publicado: (2016)

Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease
por: Liu, Boyan, et al.
Publicado: (2016)

Biosynthetic mechanisms of isoflavone accumulation affected by different growth patterns in Astragalus mongholicus products
por: Zhang, Fusheng, et al.
Publicado: (2022)

Rapid identification of growth years and profiling of bioactive ingredients in Astragalus membranaceus var. mongholicus (Huangqi) roots from Hunyuan, Shanxi
por: Peng, Hua-Sheng, et al.
Publicado: (2017)

Chemical Discrimination of Astragalus mongholicus and Astragalus membranaceus Based on Metabolomics Using UHPLC-ESI-Q-TOF-MS/MS Approach
por: Wang, Yumei, et al.
Publicado: (2019)

Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Hypertensive Renal Damage through lncRNA-mRNA Coexpression Network
por: Zhou, Le, et al.
Publicado: (2022)

Salvia miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications
por: Ren, Jie, et al.
Publicado: (2019)

Aromatic Constituents from the Stems of Astragalus membranaceus (Fisch.) Bge. var. Mongholicus (Bge.) Hsiao
por: Hao, Jia, et al.
Publicado: (2016)

UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings
por: Liu, Yang, et al.
Publicado: (2020)

Astragalus mongholicus Bunge (Fabaceae): Bioactive Compounds and Potential Therapeutic Mechanisms Against Alzheimer’s Disease
por: Dong, Qianyu, et al.
Publicado: (2022)

Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity
por: Li, Yuan, et al.
Publicado: (2019)

A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots
por: Chen, Yi, et al.
Publicado: (2022)

Computational pharmacological comparison of Salvia miltiorrhiza and Panax notoginseng used in the therapy of cardiovascular diseases
por: ZHENG, CHUN-SONG, et al.
Publicado: (2013)

Salvia miltiorrhiza in thorax and abdomainal organ fibrosis: A review of its pharmacology
por: Yang, Zhao, et al.
Publicado: (2022)

Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology
por: Li, Peng, et al.
Publicado: (2021)

A Network Pharmacology Technique to Investigate the Synergistic Mechanisms of Salvia miltiorrhiza and Radix puerariae in Treatment of Cardio-Cerebral Vascular Diseases
por: Ma, Yang, et al.
Publicado: (2020)

Subcritical Water Extraction of Salvia miltiorrhiza
por: Kapalavavi, Brahmam, et al.
Publicado: (2021)

Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza
por: Li, Bin, et al.
Publicado: (2017)

Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF-β/TβR and Imp7/8
por: Wu, Chao, et al.
Publicado: (2018)

Retracted: Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Hypertensive Renal Damage through lncRNA-mRNA Coexpression Network
por: International, BioMed Research
Publicado: (2023)

Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway
por: Zhang, Mu-Xin, et al.
Publicado: (2023)

Promoting the Development of Astragalus mongholicus Bunge Industry in Guyang County (China) Based on MaxEnt and Remote Sensing
por: Zhang, Ru, et al.
Publicado: (2022)

Accumulation of Astragalosides and Related Gene Expression in Different Organs of Astragalus Membranaceus Bge. var Mongholicus (Bge.)
por: Kim, Yeon Bok, et al.
Publicado: (2014)

Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains
por: Bi, Yaqiong, et al.
Publicado: (2020)

The bacterial consortia promote plant growth and secondary metabolite accumulation in Astragalus mongholicus under drought stress
por: Lin, Yixian, et al.
Publicado: (2022)

Mechanism of Salvia miltiorrhiza Bge. for the Treatment of Ischemic Stroke Based on Bioinformatics and Network Pharmacology
por: Wu, Jiaqi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fvrrs69ghdjpgl1nadiktep2j7