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Extracellular Matrix-Induced GM-CSF and Hypoxia Promote Immune Control of Mycobacterium tuberculosis in Human In Vitro Granulomas

Several in vitro cellular models have been developed with the aim to reproduce and dissect human granulomatous responses, the hallmark of tuberculosis (TB) immunopathogenesis. In that context, we compared two- (2D) versus three-dimensional (3D) granuloma models resulting from infection of human peri...

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Detalles Bibliográficos
Autores principales:	Arbués, Ainhoa, Schmidiger, Sarah, Kammüller, Michael, Portevin, Damien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486295/ https://www.ncbi.nlm.nih.gov/pubmed/34603299 http://dx.doi.org/10.3389/fimmu.2021.727508

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