Cargando…

Regulation of Apelin-13 on Bcl-2 and Caspase-3 and Its Effects on Adipocyte Apoptosis

OBJECTIVE: The effects of apelin-13 on the expression of Bcl-2 and caspase-3 factors and the apoptosis of adipocytes were studied at the cellular and animal levels. METHODS: 3T3-L1 preadipocytes were cultured and grouped. The third-generation cells were added to the control DMSO solvent and amidatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhan, Wang, Sha, He, Yiwei, Li, Qiong, Gao, Guoying, Tong, Guoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486539/ https://www.ncbi.nlm.nih.gov/pubmed/34603462 http://dx.doi.org/10.1155/2021/1687919

Ejemplares similares

Amidation-Modified Apelin-13 Regulates PPARγ and Perilipin to Inhibit Adipogenic Differentiation and Promote Lipolysis
por: Wang, Sha, et al.
Publicado: (2021)

Activation of Bcl-2-Caspase-9 Apoptosis Pathway in the Testis of Asthmatic Mice
por: Xu, Wenyuan, et al.
Publicado: (2016)

Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury
por: Shao, Zi-Qi, et al.
Publicado: (2020)

Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9
por: Marsden, Vanessa S., et al.
Publicado: (2004)

Apelin-13 Protects Neurons by Attenuating Early-Stage Postspinal Cord Injury Apoptosis In Vitro
por: Lin, Taotao, et al.
Publicado: (2022)

Temporal Expression of Apelin/Apelin Receptor in Ischemic Stroke and its Therapeutic Potential
por: Wu, Yili, et al.
Publicado: (2017)

Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis
por: Lu, Dinggui, et al.
Publicado: (2022)

Apelin-13 Decreases Lipid Storage in Hypertrophic Adipocytes In Vitro Through the Upregulation of AQP7 Expression by the PI3K Signaling Pathway
por: Guo, Mei, et al.
Publicado: (2014)

Lateral intracerebroventricular injection of Apelin-13 inhibits apoptosis after cerebral ischemia/reperfusion injury
por: Yan, Xiao-ge, et al.
Publicado: (2015)

Regulation of Apelin and Its Receptor Expression in Adipose Tissues of Obesity Rats with Hypertension and Cultured 3T3-L1 Adipocytes
por: Wu, Hongxian, et al.
Publicado: (2014)

Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Placenta
por: Hamza, Reham Z., et al.
Publicado: (2021)

Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction
por: Zhang, Lu, et al.
Publicado: (2019)

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
por: Keuper, M, et al.
Publicado: (2013)

Regulation of survivin and caspase/Bcl-2/Cyto-C signaling by TDB-6 induces apoptosis of colorectal carcinoma LoVo cells
por: Shi, Xianpeng, et al.
Publicado: (2022)

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
por: Marzo, Isabel, et al.
Publicado: (1998)

Apelin-13: A Promising Biomarker for Multiple Sclerosis?
por: Alpua, Murat, et al.
Publicado: (2018)

Apelin-13 as a Potential Biomarker in Critical Illness
por: Gergics, Marin, et al.
Publicado: (2023)

[Pyr(1)]Apelin-13((1–12)) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr(1)]Apelin-13
por: Yang, Peiran, et al.
Publicado: (2017)

Apelin and Apelin Receptor in Follicular Granulosa Cells of Buffalo Ovaries: Expression and Regulation of Steroidogenesis
por: Shokrollahi, Borhan, et al.
Publicado: (2022)

On Methods for the Measurement of the Apelin Receptor Ligand Apelin
por: Janssens, Peter, et al.
Publicado: (2022)

Effect of troxerutin on apelin-13, apelin receptors (APJ), and ovarian histological changes in the offspring of high-fat diet fed rats
por: Mehri, Keyvan, et al.
Publicado: (2019)

Disabled‐1 is down‐regulated in clinical breast cancer and regulates cell apoptosis through NF‐κB/Bcl‐2/caspase‐9
por: Cao, Rang‐Juan, et al.
Publicado: (2018)

Apelin and apelin receptor expression in renal cell carcinoma
por: Tolkach, Yuri, et al.
Publicado: (2019)

Apelin13/APJ promotes proliferation of colon carcinoma by activating Notch3 signaling pathway
por: Chen, Tong, et al.
Publicado: (2017)

IP10-CDR3 Reduces The Viability And Induces The Apoptosis Of Ovarian Cancer Cells By Down-Regulating The Expression Of Bcl-2 And Caspase 3
por: Chen, Qi, et al.
Publicado: (2019)

Retracted: Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis
por: Markers, Disease
Publicado: (2023)

Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy
por: Faião-Flores, Fernanda, et al.
Publicado: (2013)

Upregulation of DAPK contributes to homocysteine-induced endothelial apoptosis via the modulation of Bcl2/Bax and activation of caspase 3
por: Tian, Xin, et al.
Publicado: (2016)

Apelin-13 regulates electrical activity in the globus pallidus and induces postural changes in rats
por: Wang, Ying, et al.
Publicado: (2021)

Effects of intracerebroventricular injection of apelin-13 on food intake in broiler chicks
por: Amini Zadeh, Razieh, et al.
Publicado: (2023)

The beneficial roles of apelin-13/APJ system in cerebral ischemia: Pathogenesis and therapeutic strategies
por: Li, Jiabin, et al.
Publicado: (2022)

Follistatin‐like protein 5 inhibits hepatocellular carcinoma progression by inducing caspase‐dependent apoptosis and regulating Bcl‐2 family proteins
por: Li, Chunlei, et al.
Publicado: (2018)

Research Progress on Mechanism of Neuroprotective Roles of Apelin-13 in Prevention and Treatment of Alzheimer’s Disease
por: Wan, Teng, et al.
Publicado: (2021)

Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway
por: Jia, Geng, et al.
Publicado: (2015)

Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53
por: Yao, Chunping, et al.
Publicado: (2017)

Fish oil administration mediates apoptosis of Walker 256 tumor cells by modulation of p53, Bcl-2, caspase-7 and caspase-3 protein expression
por: Borghetti, Gina, et al.
Publicado: (2015)

Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis
por: Chen, Li, et al.
Publicado: (2015)

The Effects of Apelin and Elabela Ligands on Apelin Receptor Distinct Signaling Profiles
por: Jiang, Yunlu, et al.
Publicado: (2021)

BCL6 regulates brown adipocyte dormancy to maintain thermogenic reserve and fitness
por: Kutyavin, Vassily I., et al.
Publicado: (2019)

Preferential apelin-13 production by the proprotein convertase PCSK3 is implicated in obesity()
por: Shin, Kyungsoo, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ml1b48b4b8eqag54q6iqcigkrt