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Advances in optical gastrointestinal endoscopy: a technical review

Optical endoscopy is the primary diagnostic and therapeutic tool for management of gastrointestinal (GI) malignancies. Most GI neoplasms arise from precancerous lesions; thus, technical innovations to improve detection and diagnosis of precancerous lesions and early cancers play a pivotal role in im...

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Autores principales: Tang, Yubo, Anandasabapathy, Sharmila, Richards‐Kortum, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486567/
https://www.ncbi.nlm.nih.gov/pubmed/32915503
http://dx.doi.org/10.1002/1878-0261.12792
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author Tang, Yubo
Anandasabapathy, Sharmila
Richards‐Kortum, Rebecca
author_facet Tang, Yubo
Anandasabapathy, Sharmila
Richards‐Kortum, Rebecca
author_sort Tang, Yubo
collection PubMed
description Optical endoscopy is the primary diagnostic and therapeutic tool for management of gastrointestinal (GI) malignancies. Most GI neoplasms arise from precancerous lesions; thus, technical innovations to improve detection and diagnosis of precancerous lesions and early cancers play a pivotal role in improving outcomes. Over the last few decades, the field of GI endoscopy has witnessed enormous and focused efforts to develop and translate accurate, user‐friendly, and minimally invasive optical imaging modalities. From a technical point of view, a wide range of novel optical techniques is now available to probe different aspects of light–tissue interaction at macroscopic and microscopic scales, complementing white light endoscopy. Most of these new modalities have been successfully validated and translated to routine clinical practice. Herein, we provide a technical review of the current status of existing and promising new optical endoscopic imaging technologies for GI cancer screening and surveillance. We summarize the underlying principles of light–tissue interaction, the imaging performance at different scales, and highlight what is known about clinical applicability and effectiveness. Furthermore, we discuss recent discovery and translation of novel molecular probes that have shown promise to augment endoscopists' ability to diagnose GI lesions with high specificity. We also review and discuss the role and potential clinical integration of artificial intelligence‐based algorithms to provide decision support in real time. Finally, we provide perspectives on future technology development and its potential to transform endoscopic GI cancer detection and diagnosis.
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spelling pubmed-84865672021-10-07 Advances in optical gastrointestinal endoscopy: a technical review Tang, Yubo Anandasabapathy, Sharmila Richards‐Kortum, Rebecca Mol Oncol Reviews Optical endoscopy is the primary diagnostic and therapeutic tool for management of gastrointestinal (GI) malignancies. Most GI neoplasms arise from precancerous lesions; thus, technical innovations to improve detection and diagnosis of precancerous lesions and early cancers play a pivotal role in improving outcomes. Over the last few decades, the field of GI endoscopy has witnessed enormous and focused efforts to develop and translate accurate, user‐friendly, and minimally invasive optical imaging modalities. From a technical point of view, a wide range of novel optical techniques is now available to probe different aspects of light–tissue interaction at macroscopic and microscopic scales, complementing white light endoscopy. Most of these new modalities have been successfully validated and translated to routine clinical practice. Herein, we provide a technical review of the current status of existing and promising new optical endoscopic imaging technologies for GI cancer screening and surveillance. We summarize the underlying principles of light–tissue interaction, the imaging performance at different scales, and highlight what is known about clinical applicability and effectiveness. Furthermore, we discuss recent discovery and translation of novel molecular probes that have shown promise to augment endoscopists' ability to diagnose GI lesions with high specificity. We also review and discuss the role and potential clinical integration of artificial intelligence‐based algorithms to provide decision support in real time. Finally, we provide perspectives on future technology development and its potential to transform endoscopic GI cancer detection and diagnosis. John Wiley and Sons Inc. 2020-09-19 2021-10 /pmc/articles/PMC8486567/ /pubmed/32915503 http://dx.doi.org/10.1002/1878-0261.12792 Text en © 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Tang, Yubo
Anandasabapathy, Sharmila
Richards‐Kortum, Rebecca
Advances in optical gastrointestinal endoscopy: a technical review
title Advances in optical gastrointestinal endoscopy: a technical review
title_full Advances in optical gastrointestinal endoscopy: a technical review
title_fullStr Advances in optical gastrointestinal endoscopy: a technical review
title_full_unstemmed Advances in optical gastrointestinal endoscopy: a technical review
title_short Advances in optical gastrointestinal endoscopy: a technical review
title_sort advances in optical gastrointestinal endoscopy: a technical review
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486567/
https://www.ncbi.nlm.nih.gov/pubmed/32915503
http://dx.doi.org/10.1002/1878-0261.12792
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