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Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

Neuroendocrine carcinomas (NEC) are tumors expressing markers of neuronal differentiation that can arise at different anatomic sites but have strong histological and clinical similarities. Here we report the chromatin landscapes of a range of human NECs and show convergence to the activation of a co...

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Detalles Bibliográficos
Autores principales: Cejas, Paloma, Xie, Yingtian, Font-Tello, Alba, Lim, Klothilda, Syamala, Sudeepa, Qiu, Xintao, Tewari, Alok K., Shah, Neel, Nguyen, Holly M., Patel, Radhika A., Brown, Lisha, Coleman, Ilsa, Hackeng, Wenzel M., Brosens, Lodewijk, Dreijerink, Koen M. A., Ellis, Leigh, Alaiwi, Sarah Abou, Seo, Ji-Heui, Baca, Sylvan, Beltran, Himisha, Khani, Francesca, Pomerantz, Mark, Dall’Agnese, Alessandra, Crowdis, Jett, Van Allen, Eliezer M., Bellmunt, Joaquim, Morrisey, Colm, Nelson, Peter S., DeCaprio, James, Farago, Anna, Dyson, Nicholas, Drapkin, Benjamin, Liu, X. Shirley, Freedman, Matthew, Haffner, Michael C., Corey, Eva, Brown, Myles, Long, Henry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486778/
https://www.ncbi.nlm.nih.gov/pubmed/34599169
http://dx.doi.org/10.1038/s41467-021-26042-z