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Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells
Congenital cataracts are the leading cause of childhood blindness. To date, surgical removal of cataracts is the only established treatment, but surgery is associated with multiple complications, which often lead to visual impairment. Therefore, mechanistic studies and drug-candidate screening have...
Autores principales: | Lyu, Danni, Zhang, Lifang, Qin, Zhenwei, Ni, Shuang, Li, Jiayong, Lu, Bing, Hao, Shengjie, Tang, Qiaomei, Yin, Houfa, Chen, Zhijian, Yan, Yong-Bin, Ji, Junfeng, He, Jiliang, Nagy, Andras, Fu, Qiuli, Yao, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486789/ https://www.ncbi.nlm.nih.gov/pubmed/34599192 http://dx.doi.org/10.1038/s41536-021-00171-x |
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