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Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

Congenital cataracts are the leading cause of childhood blindness. To date, surgical removal of cataracts is the only established treatment, but surgery is associated with multiple complications, which often lead to visual impairment. Therefore, mechanistic studies and drug-candidate screening have...

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Detalles Bibliográficos
Autores principales: Lyu, Danni, Zhang, Lifang, Qin, Zhenwei, Ni, Shuang, Li, Jiayong, Lu, Bing, Hao, Shengjie, Tang, Qiaomei, Yin, Houfa, Chen, Zhijian, Yan, Yong-Bin, Ji, Junfeng, He, Jiliang, Nagy, Andras, Fu, Qiuli, Yao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486789/
https://www.ncbi.nlm.nih.gov/pubmed/34599192
http://dx.doi.org/10.1038/s41536-021-00171-x

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