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Viral polymerase binding and broad-spectrum antiviral activity of molnupiravir against human seasonal coronaviruses

Endemic seasonal coronaviruses cause morbidity and mortality in a subset of patients, but no specific treatment is available. Molnupiravir is a promising pipeline antiviral drug for treating SARS-CoV-2 infection potentially by targeting RNA-dependent RNA polymerase (RdRp). This study aims to evaluat...

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Detalles Bibliográficos
Autores principales:	Wang, Yining, Li, Pengfei, Solanki, Kundan, Li, Yang, Ma, Zhongren, Peppelenbosch, Maikel P., Baig, Mirza S., Pan, Qiuwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486977/ https://www.ncbi.nlm.nih.gov/pubmed/34619630 http://dx.doi.org/10.1016/j.virol.2021.09.009

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