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Hemin activation abrogates Mycoplasma hyorhinis replication in chronically infected prostate cancer cells via heme oxygenase‐1 induction

Mycoplasma hyorhinis (M. hyorhinis) lacks a cell wall and resists multiple antibiotics. We describe here the striking > 90% inhibitory effect of hemin, a natural inducer of the cytoprotective enzyme heme oxygenase‐1 (HO‐1), on M. hyorhinis replication in chronically infected LNCaP prostate cancer...

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Detalles Bibliográficos
Autores principales: Huang, Hanxia, Dabrazhynetskaya, Alena, Pluznik, Jacob, Zheng, Jiwen, Wu, Yong, Chizhikov, Vladimir, Buehler, Paul W., Yamada, Kenneth M., Dhawan, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487054/
https://www.ncbi.nlm.nih.gov/pubmed/34375508
http://dx.doi.org/10.1002/2211-5463.13271