Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy

Fukuyama congenital muscular dystrophy (FCMD) is a severe, intractable genetic disease that affects the skeletal muscle, eyes, and brain and is attributed to a defect in alpha dystroglycan (αDG) O-mannosyl glycosylation. We previously established disease models of FCMD; however, they did not fully r...

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Detalles Bibliográficos
Autores principales: Taniguchi-Ikeda, Mariko, Koyanagi-Aoi, Michiyo, Maruyama, Tatsuo, Takaori, Toru, Hosoya, Akiko, Tezuka, Hiroyuki, Nagase, Shotaro, Ishihara, Takuma, Kadoshima, Taisuke, Muguruma, Keiko, Ishigaki, Keiko, Sakurai, Hidetoshi, Mizoguchi, Akira, Novitch, Bennett G., Toda, Tatsushi, Watanabe, Momoko, Aoi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487058/
https://www.ncbi.nlm.nih.gov/pubmed/34632335
http://dx.doi.org/10.1016/j.isci.2021.103140

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