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The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease

Parkinson's disease (PD) is a chronic neurodegenerative disorder that is characterized by motor symptoms as a result of a loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), accompanied by chronic neuroinflammation, oxidative stress, formation of α-synuclein aggregates. Ce...

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Detalles Bibliográficos
Autores principales:	Zhang, Chenyu, Zhao, Miao, Wang, Bingwei, Su, Zhijie, Guo, Bingbing, Qin, Lihua, Zhang, Weiguang, Zheng, Ruimao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487081/ https://www.ncbi.nlm.nih.gov/pubmed/34600334 http://dx.doi.org/10.1016/j.redox.2021.102134

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