HDAC inhibition induces EMT and alterations in cellular iron homeostasis to augment ferroptosis sensitivity in SW13 cells

Epithelial-to-mesenchymal transition (EMT) is an essential mechanism for development and wound healing, but in cancer it also mediates the progression and spread of aggressive tumors while increasing therapeutic resistance. Adoption of a mesenchymal state is also associated with increased iron uptak...

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Detalles Bibliográficos
Autores principales: Oliveira, Thais, Hermann, Evan, Lin, Daniel, Chowanadisai, Winyoo, Hull, Elizabeth, Montgomery, McKale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487084/
https://www.ncbi.nlm.nih.gov/pubmed/34600336
http://dx.doi.org/10.1016/j.redox.2021.102149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487084/
https://www.ncbi.nlm.nih.gov/pubmed/34600336
http://dx.doi.org/10.1016/j.redox.2021.102149

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