Enhanced Alcoholic Liver Disease in Mice with Intestine-specific Farnesoid X Receptor Deficiency

Alcoholic fatty liver disease (AFLD) is one of the major causes of liver morbidity and mortality worldwide. We have previously shown that whole-body, but not hepatocyte-specific, deficiency of farnesoid X receptor (FXR) in mice worsens AFLD, suggesting that extra-hepatic FXR deficiency is critical f...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Mingxing, Kong, Bo, Zhang, Min, Rizzolo, Daniel, Armstrong, Laura E., Schumacher, Justin D., Chow, Monica D., Lee, Yi-Horng, Joseph, Laurie B., Stofan, Mary, Zhang, Lanjing, Guo, Grace L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487140/
https://www.ncbi.nlm.nih.gov/pubmed/32404932
http://dx.doi.org/10.1038/s41374-020-0439-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487140/
https://www.ncbi.nlm.nih.gov/pubmed/32404932
http://dx.doi.org/10.1038/s41374-020-0439-y

Ejemplares similares