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Enhanced Alcoholic Liver Disease in Mice with Intestine-specific Farnesoid X Receptor Deficiency
Alcoholic fatty liver disease (AFLD) is one of the major causes of liver morbidity and mortality worldwide. We have previously shown that whole-body, but not hepatocyte-specific, deficiency of farnesoid X receptor (FXR) in mice worsens AFLD, suggesting that extra-hepatic FXR deficiency is critical f...
Autores principales: | Huang, Mingxing, Kong, Bo, Zhang, Min, Rizzolo, Daniel, Armstrong, Laura E., Schumacher, Justin D., Chow, Monica D., Lee, Yi-Horng, Joseph, Laurie B., Stofan, Mary, Zhang, Lanjing, Guo, Grace L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487140/ https://www.ncbi.nlm.nih.gov/pubmed/32404932 http://dx.doi.org/10.1038/s41374-020-0439-y |
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