Cargando…

Psilocin, LSD, mescaline, and DOB all induce broadband desynchronization of EEG and disconnection in rats with robust translational validity

Serotonergic psychedelics are recently gaining a lot of attention as a potential treatment of several neuropsychiatric disorders. Broadband desynchronization of EEG activity and disconnection in humans have been repeatedly shown; however, translational data from animals are completely lacking. There...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vejmola, Čestmír, Tylš, Filip, Piorecká, Václava, Koudelka, Vlastimil, Kadeřábek, Lukáš, Novák, Tomáš, Páleníček, Tomáš
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487430/ https://www.ncbi.nlm.nih.gov/pubmed/34601495 http://dx.doi.org/10.1038/s41398-021-01603-4

Ejemplares similares

Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats
por: Tylš, Filip, et al.
Publicado: (2023)

The Effect of Psilocin on Memory Acquisition, Retrieval, and Consolidation in the Rat
por: Rambousek, Lukas, et al.
Publicado: (2014)

Electrical Source Imaging in Freely Moving Rats: Evaluation of a 12-Electrode Cortical Electroencephalography System
por: Jiricek, Stanislav, et al.
Publicado: (2021)

Real-Time Excitation of Slow Oscillations during Deep Sleep Using Acoustic Stimulation
por: Piorecky, Marek, et al.
Publicado: (2021)

Apnea Detection in Polysomnographic Recordings Using Machine Learning Techniques
por: Piorecky, Marek, et al.
Publicado: (2021)

Lysergic Acid Diethylamide and Mescaline in Experimental Psychiatry
por: Freedman, Daniel X.
Publicado: (1957)

Mephedrone (4-Methylmethcathinone): Acute Behavioral Effects, Hyperthermic, and Pharmacokinetic Profile in Rats
por: Šíchová, Klára, et al.
Publicado: (2018)

Simultaneous fMRI-EEG-Based Characterisation of NREM Parasomnia Disease: Methods and Limitations
por: Piorecky, Marek, et al.
Publicado: (2020)

Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats—pharmacokinetics, effects on behaviour and thermoregulation
por: Syrová, Kateřina, et al.
Publicado: (2023)

Psilocybin—Mediated Attenuation of Gamma Band Auditory Steady-State Responses (ASSR) Is Driven by the Intensity of Cognitive and Emotional Domains of Psychedelic Experience
por: Viktorin, Vojtěch, et al.
Publicado: (2022)

PM506. Psilocybin Clinical Trial: Acute Effects and its relationship to the brain activity as measured by quantitative EEG
por: Tyls, Filip, et al.
Publicado: (2016)

PM502. Effect of psilocybin on EEG brain connectivity in healthy volunteers – preliminary report
por: Palenicek, Tomas, et al.
Publicado: (2016)

The fumarate salts of the N-isopropyl-N-methyl derivatives of DMT and psilocin
por: Chadeayne, Andrew R., et al.
Publicado: (2019)

Structure Elucidation and Spectroscopic Analysis of Chromophores Produced by Oxidative Psilocin Dimerization
por: Lenz, Claudius, et al.
Publicado: (2021)

Assessment of Bioactivity‐Modulating Pseudo‐Ring Formation in Psilocin and Related Tryptamines
por: Lenz, Claudius, et al.
Publicado: (2022)

Clinical significance of PI3 and HLA-DOB as potential prognostic predicators for ovarian cancer
por: Li, Yanrong, et al.
Publicado: (2020)

The disconnected: COVID-19 and disparities in access to quality broadband for higher education students
por: Cullinan, John, et al.
Publicado: (2021)

Biochemical, Histopathological and Morphological Profiling of a Rat Model of Early Immune Stimulation: Relation to Psychopathology
por: Kubesova, Anna, et al.
Publicado: (2015)

Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain
por: Spain, Aisling, et al.
Publicado: (2015)

Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus)
por: Ivy-Israel, Natascha M. D., et al.
Publicado: (2020)

The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update
por: Malagraba, Gianluca, et al.
Publicado: (2022)

Direct Phosphorylation of Psilocin Enables Optimized cGMP Kilogram-Scale Manufacture of Psilocybin
por: Kargbo, Robert B., et al.
Publicado: (2020)

Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice
por: Thomas, Christopher W., et al.
Publicado: (2022)

Effects of ketamine optical isomers, psilocybin, psilocin and norpsilocin on time estimation and cognition in rats
por: Popik, Piotr, et al.
Publicado: (2022)

De novo sequencing and analysis of Lophophora williamsii transcriptome, and searching for putative genes involved in mescaline biosynthesis
por: Ibarra-Laclette, Enrique, et al.
Publicado: (2015)

Receptor Interaction Profiles of 4-Alkoxy-3,5-Dimethoxy-Phenethylamines (Mescaline Derivatives) and Related Amphetamines
por: Kolaczynska, Karolina E., et al.
Publicado: (2022)

Cardiac effects of ephedrine, norephedrine, mescaline, and 3,4-methylenedioxymethamphetamine (MDMA) in mouse and human atrial preparations
por: Neumann, Joachim, et al.
Publicado: (2022)

Acute DOB and PMA Administration Impairs Motor and Sensorimotor Responses in Mice and Causes Hallucinogenic Effects in Adult Zebrafish
por: Tirri, Micaela, et al.
Publicado: (2020)

The epidemiology of mescaline use: Pattern of use, motivations for consumption, and perceived consequences, benefits, and acute and enduring subjective effects
por: Uthaug, Malin Vedøy, et al.
Publicado: (2021)

MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil
por: Castelli, Erick C., et al.
Publicado: (2022)

DoMYB5 and DobHLH24, Transcription Factors Involved in Regulating Anthocyanin Accumulation in Dendrobium officinale
por: Yang, Kun, et al.
Publicado: (2023)

Research on Acute Toxicity and the Behavioral Effects of Methanolic Extract from Psilocybin Mushrooms and Psilocin in Mice
por: Zhuk, Olga, et al.
Publicado: (2015)

Discourses on disconnectivity and the right to disconnect
por: Hesselberth, Pepita
Publicado: (2017)

Psilocybin desynchronizes brain networks
por: Siegel, Joshua S, et al.
Publicado: (2023)

Characterization of the major histocompatibility complex class II DOB, DPB1, and DQB1 alleles in cynomolgus macaques of Vietnamese origin
por: Ling, Fei, et al.
Publicado: (2010)

Study on Low-Temperature and Fatigue Performance of High RAP Content Hot Recycled Asphalt Mixture Based on the Degree of Blending (DOB)
por: Wu, Jianming, et al.
Publicado: (2022)

Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis
por: Poliwoda, Anna, et al.
Publicado: (2020)

Psilacetin derivatives: fumarate salts of the methyl–ethyl, methyl–allyl and diallyl variants of the psilocin prodrug
por: Pham, Duyen N. K., et al.
Publicado: (2021)

Novel, unifying mechanism for mescaline in the central nervous system: Electrochemistry, catechol redox metabolite, receptor, cell signaling and structure activity relationships
por: Kovacic, Peter, et al.
Publicado: (2009)

Synchronization and desynchronization in epilepsy: controversies and hypotheses
por: Jiruska, Premysl, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8vj93uv8qofkspm1r5gk0c4luv