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Effect of EPA on Hsp90 and GRα protein expression in multiple myeloma drug-resistant cells

BACKGROUND: Approximately 20% of MM patients harbor glucocorticoid (GC) resistance and are not responsive to therapeutic effect. Chaperoneheat-shock proteins Hsp90 is needed for ligand docking, The imbalance of Hsp90/GRα (glucocorticoid receptor α) may be an important cause of GC resistance. Recent...

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Detalles Bibliográficos
Autores principales:	Wu, Shenghao, Chen, Yuemiao, Wang, Xueshuang, Weng, Shanshan, Zhou, Wenjin, Liu, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487534/ https://www.ncbi.nlm.nih.gov/pubmed/34600510 http://dx.doi.org/10.1186/s12885-021-08804-6

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