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Anti-inflammatory efficacy of Berberine Nanomicelle for improvement of cerebral ischemia: formulation, characterization and evaluation in bilateral common carotid artery occlusion rat model
BACKGROUND: Berberine (BBR) is a plant alkaloid that possesses anti-inflammatory and anti-oxidant effects with low oral bioavailability. In this study, micelle formulation of BBR was investigated to improve therapeutic efficacy and examined its effect on the secretion of inflammatory cytokines in ce...
Autores principales: | Azadi, Roza, Mousavi, Seyyedeh Elaheh, Kazemi, Negar Motakef, Yousefi-Manesh, Hasan, Rezayat, Seyed Mahdi, Jaafari, Mahmoud Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487542/ https://www.ncbi.nlm.nih.gov/pubmed/34600570 http://dx.doi.org/10.1186/s40360-021-00525-7 |
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