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Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes

BACKGROUND: Rheumatoid arthritis is a progressive and systemic autoimmune disease seriously compromises human health. Fibroblast like synoviocytes are the major effectors of proliferation and inflammation in rheumatoid arthritis synovial tissue. Shikonin has anti-inflammatory and immunomodulatory ac...

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Detalles Bibliográficos
Autores principales:	He, Lianhua, Luan, Huijie, He, Juan, Zhang, Miaomiao, Qin, Qingxia, Hu, Yiping, Cai, Yueming, Sun, Desheng, Shi, Yu, Wang, Qingwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487562/ https://www.ncbi.nlm.nih.gov/pubmed/34600581 http://dx.doi.org/10.1186/s13020-021-00510-6

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