Genetic diversity of SARS-CoV-2 in South America: demographic history and structuration signals

In 2020, the emergence of SARS-CoV-2 caused a global public health crisis with significant mortality rates and a large socioeconomic burden. The rapid spread of this new virus has led to the appearance of new variants, making the characterization and monitoring of genetic diversity necessary to unde...

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Detalles Bibliográficos
Autores principales: Buitrago, Sindy P., Garzón-Ospina, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487618/
https://www.ncbi.nlm.nih.gov/pubmed/34604926
http://dx.doi.org/10.1007/s00705-021-05258-w
Descripción
Sumario:In 2020, the emergence of SARS-CoV-2 caused a global public health crisis with significant mortality rates and a large socioeconomic burden. The rapid spread of this new virus has led to the appearance of new variants, making the characterization and monitoring of genetic diversity necessary to understand the population dynamics and evolution of the virus. Here, a population-genetics-based study was performed starting with South American genome sequences available in the GISAID database to investigate the genetic diversity of SARS-CoV-2 on this continent and the evolutionary mechanisms that modulate it. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00705-021-05258-w.

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