Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study

Acute kidney injury (AKI) affects up to 30% of patients undergoing cardiac surgery, leading to increased in-hospital and long-term morbidity and mortality. Teprasiran is a novel small interfering RNA that temporarily inhibits p53-mediated cell death that underlies AKI. METHODS: This prospective, mul...

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Detalles Bibliográficos
Autores principales: Thielmann, Matthias, Corteville, David, Szabo, Gabor, Swaminathan, Madhav, Lamy, Andre, Lehner, Lukas J., Brown, Craig D., Noiseux, Nicolas, Atta, Mohamed G., Squiers, Elizabeth C., Erlich, Shai, Rothenstein, Daniel, Molitoris, Bruce, Mazer, C. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487715/
https://www.ncbi.nlm.nih.gov/pubmed/34474590
http://dx.doi.org/10.1161/CIRCULATIONAHA.120.053029

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