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Discovery and Features of an Alkylating Signature in Colorectal Cancer

Several risk factors have been established for colorectal cancer, yet their direct mutagenic effects in patients' tumors remain to be elucidated. Here, we leveraged whole-exome sequencing data from 900 colorectal cancer cases that had occurred in three U.S.-wide prospective studies with extensi...

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Detalles Bibliográficos
Autores principales:	Gurjao, Carino, Zhong, Rong, Haruki, Koichiro, Li, Yvonne Y., Spurr, Liam F., Lee-Six, Henry, Reardon, Brendan, Ugai, Tomotaka, Zhang, Xuehong, Cherniack, Andrew D., Song, Mingyang, Van Allen, Eliezer M., Meyerhardt, Jeffrey A., Nowak, Jonathan A., Giovannucci, Edward L., Fuchs, Charles S., Wu, Kana, Ogino, Shuji, Giannakis, Marios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Research Briefs
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487940/ https://www.ncbi.nlm.nih.gov/pubmed/34140290 http://dx.doi.org/10.1158/2159-8290.CD-20-1656

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